Introduction：Basic information about CAS 5625-37-6|PIPES, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | PIPES |
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| CAS Number | 5625-37-6 | Molecular Weight | 670.682 |
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| Density | 1.5±0.1 g/cm3 | Boiling Point | / |
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| Molecular Formula | C16H33N4Na3O12S4 | Melting Point | >300 °C(lit.) |
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| MSDS | ChineseUSA | Flash Point | / |
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Names
| Name | 2,2'-piperazine-1,4-diylbisethanesulfonic acid |
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| Synonym | More Synonyms |
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PIPES BiologicalActivity
| Description | PIPES (1,4-Piperazinediethanesulfonic acid) is an important component of PIPES buffer agent used in biochemistry[1]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>Others >>OthersResearch Areas >>Inflammation/Immunology |
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| In Vitro | To prepare the pH PIPES buffer, 173 g of 1,4-piperazinediethanesulfonic acid are dissolved into 1 L of deionized water. The pH of the PIPES buffer is adjusted to 6.8 by adding pellets of sodium hydroxide. PIPES buffer can be used to PIPES buffer, it can prevent the glutaraldehyde fixation induced lipid loss and artifacts[1]. |
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| References | [1]. Jason Moggridge, et al. Sensitive Detection of Immunoglobulin G Stability Using in Real-Time Isothermal Differential Scanning Fluorimetry: Determinants of Protein Stability for Antibody-Based Therapeutics. Technol Cancer Res Treat. 2017 Dec;16(6):997-1005. |
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Chemical & Physical Properties
| Density | 1.5±0.1 g/cm3 |
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| Melting Point | >300 °C(lit.) |
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| Molecular Formula | C16H33N4Na3O12S4 |
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| Molecular Weight | 670.682 |
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| Exact Mass | 670.067078 |
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| PSA | 131.98000 |
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| LogP | -4.21 |
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| Index of Refraction | 1.566 |
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| InChIKey | IHPYMWDTONKSCO-UHFFFAOYSA-N |
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| SMILES | O=S(=O)(O)CCN1CCN(CCS(=O)(=O)O)CC1 |
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| Storage condition | Store at RT. |
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| Water Solubility | 0.1 M NaOH: 0.25 g/mL, clear, colorless |
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Safety Information
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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| Hazard Codes | Xi |
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| Risk Phrases | R36/37/38 |
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| Safety Phrases | S22-S24/25 |
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| RIDADR | NONH for all modes of transport |
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| WGK Germany | 3 |
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| HS Code | 29335995 |
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Customs
| HS Code | 2933599090 |
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| Summary | 2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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Articles156
More Articles
| Effect of (2)H and (18)O water isotopes in kinesin-1 gliding assay. PeerJ 2 , e284, (2014) We show for the first time the effects of heavy-hydrogen water ((2)H2O) and heavy-oxygen water (H2 (18)O) on the gliding speed of microtubules on kinesin-1 coated surfaces. Increased fractions of isot... | |
| Evidence that TSC2 acts as a transcription factor and binds to and represses the promoter of Epiregulin. Nucleic Acids Res. 42(10) , 6243-55, (2014) The TSC2 gene, mutated in patients with tuberous sclerosis complex (TSC), encodes a 200 kDa protein TSC2 (tuberin). The importance of TSC2 in the regulation of cell growth and proliferation is irrefut... | |
| Cell-free expression and in meso crystallisation of an integral membrane kinase for structure determination. Cell. Mol. Life Sci. 71(24) , 4895-910, (2014) Membrane proteins are key elements in cell physiology and drug targeting, but getting a high-resolution structure by crystallographic means is still enormously challenging. Novel strategies are in big... | |
Synonyms
| Sodium 2,2'-(1,4-piperazinediyl)diethanesulfonate 2-[4-(2-sulfoethyl)-1-piperazinyl]ethanesulfonate (3:1:1) |
| Piperazine-N,N'-bis (2-ethanesulfonic acid) |
| 1,4-Piperazinediethanesulfonic acid, sodium salt (2:3) |
| PIPES |
| 2,2'-Piperazine-1,4-diyldiethanesulfonic acid |
| 2,2'-(1,4-Piperazinediyl)diethanesulfonic acid |
| 1,4-Piperazine bis(ethanesulfonic acid) |
| 1,4-Piperazinediethanesulfonic acid sesquisodium salt |
| Piperazine-N,N'-bis(2-ethanesulfonic acid) |
| Piperazine-N,N′-bis(2-ethanesulfonic acid) |
| Piperazine-1,4-bis(2-ethanesulfonic acid) sesquisodium salt |
| 1,4-Piperazinediethanesulfonic acid |
| MFCD00006159 |
| trisodium,2-[4-(2-sulfoethyl)piperazin-1-yl]ethanesulfonate,2-[4-(2-sulfonatoethyl)piperazin-1-yl]ethanesulfonate |
| EINECS 227-057-6 |
| 2,2′-piperazine-1,4-diylbisethanesulfonic acid |
