CAS 29915-38-6|TAPS (buffer)
| Common Name | TAPS (buffer) | ||
|---|---|---|---|
| CAS Number | 29915-38-6 | Molecular Weight | 243.278 |
| Density | 1.5±0.1 g/cm3 | Boiling Point | / |
| Molecular Formula | C7H17NO6S | Melting Point | 230-235 °C (dec.) |
| MSDS | ChineseUSA | Flash Point | 110 °C |
Names
| Name | 3-[[1,3-dihydroxy-2-(hydroxymethyl)propan-2-yl]amino]propane-1-sulfonic acid |
|---|---|
| Synonym | More Synonyms |
TAPS (buffer) BiologicalActivity
| Description | TAPS is a biological buffer, remain lysozyme native structure intact and prevents thermal denaturation against high temperatures. TAPS exhibits pKa value of 8.1, while the half-maximum values of connexin channel activity is 8.5 (pH)[1][2]. |
|---|---|
| Related Catalog | Research Areas >>OthersSignaling Pathways >>Others >>Others |
| References | [1]. Pannuru P, et al. The effects of biological buffers TRIS, TAPS, TES on the stability of lysozyme. Int J Biol Macromol. 2018 Jun;112:720-727. [2]. Bevans CG, et al. Regulation of connexin channels by pH. Direct action of the protonated form of taurine and other aminosulfonates. J Biol Chem. 1999 Feb 5;274(6):3711-9.Bevans CG, et al. Regulation of connexin channels by pH. Direct action of the protonated form of taurine and other aminosulfonates. J Biol Chem. 1999 Feb 5;274(6):3711-9. |
Chemical & Physical Properties
| Density | 1.5±0.1 g/cm3 |
|---|---|
| Melting Point | 230-235 °C (dec.) |
| Molecular Formula | C7H17NO6S |
| Molecular Weight | 243.278 |
| Flash Point | 110 °C |
| Exact Mass | 243.077652 |
| PSA | 135.47000 |
| LogP | -2.40 |
| Index of Refraction | 1.561 |
| InChIKey | YNLCVAQJIKOXER-UHFFFAOYSA-N |
| SMILES | O=S(=O)(O)CCCNC(CO)(CO)CO |
| Storage condition | Store at RT. |
| Stability | Stable. Incompatible with strong oxidizing agents |
| Water Solubility | Soluble |
Safety Information
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| Hazard Codes | Xi |
| Risk Phrases | R36/37/38:Irritating to eyes, respiratory system and skin . |
| Safety Phrases | S22-S24/25 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| HS Code | 29221980 |
Customs
| HS Code | 29221980 |
|---|
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Synonyms
| 1-Propanesulfonic acid, 3-[[2-hydroxy-1,1-bis(hydroxymethyl)ethyl]amino]- |
| [(2-Hydroxy-1,1-bis(hydroxymethyl)ethyl)amino]-1-propanesulfonic acid |
| 3-((1,3-Dihydroxy-2-(hydroxymethyl)propan-2-yl)amino)propane-1-sulfonic acid |
| N-Tris(Hydroxymethy)methyl-3-aminopropanesulfonic acid |
| T3A |
| 3-{[1,3-dihydroxy-2-(hydroxymethyl)propan-2-yl]amino}propane-1-sulfonic acid |
| N-Tris(hydroxymethyl)methyl-3-aminopropanesulfonic Acid [Good's buffer component |
| EINECS 249-954-1 |
| N-[Tris（hydroxymethyl）metyl]-3-aminopropanesulfonic acid |
| 3-(TRIS(HYDROXYMETHYL)METHYLAMINO)-1-PROPANESULFONIC ACID |
| 3-{[1,3-Dihydroxy-2-(hydroxymethyl)-2-propanyl]amino}-1-propanesulfonic acid |
| MFCD00007538 |
| TAPS |
| 3-[N-Tris-(hydroxymethyl)methylamino]propanesulphonic (TAPS) |
| N-Tris(hydroxymethyl)methyl-3-aminopropanesulfonic acid |
