CAS 81-82-3|COUMACHLOR

Introduction：Basic information about CAS 81-82-3|COUMACHLOR, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Chemical & Physical Properties
3. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
4. Safety Information
5. Articles9
6. Synonyms

Common Name	COUMACHLOR
CAS Number	81-82-3	Molecular Weight	342.773
Density	1.4±0.1 g/cm3	Boiling Point	543.1±50.0 °C at 760 mmHg
Molecular Formula	C₁₉H₁₅ClO₄	Melting Point	168-170 °C(lit.)
MSDS	ChineseUSA	Flash Point	282.3±30.1 °C
Symbol	GHS08	Signal Word	Warning

Names

Name	coumachlor
Synonym	More Synonyms

Chemical & Physical Properties

Density	1.4±0.1 g/cm3
Boiling Point	543.1±50.0 °C at 760 mmHg
Melting Point	168-170 °C(lit.)
Molecular Formula	C₁₉H₁₅ClO₄
Molecular Weight	342.773
Flash Point	282.3±30.1 °C
Exact Mass	342.065887
PSA	67.51000
LogP	4.01
Vapour Pressure	0.0±1.5 mmHg at 25°C
Index of Refraction	1.641
InChIKey	DEKWZWCFHUABHE-UHFFFAOYSA-N
SMILES	CC(=O)CC(c1ccc(Cl)cc1)c1c(O)c2ccccc2oc1=O

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: GN4830000

CHEMICAL NAME :: Coumarin, 3-(alpha-acetonyl-p-chlorobenzyl)-4-hydroxy-

CAS REGISTRY NUMBER :: 81-82-3

BEILSTEIN REFERENCE NO. :: 1689759

LAST UPDATED :: 199612

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C19-H15-Cl-O4

MOLECULAR WEIGHT :: 342.79

WISWESSER LINE NOTATION :: T66 BOVJ DY1V1&R DG& EQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 187 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,186,1991

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 33 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,186,1991

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 392 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique. (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France) V.9- 1974- Volume(issue)/page/year: 30,531,1995

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 221 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique. (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France) V.9- 1974- Volume(issue)/page/year: 30,531,1995

Safety Information

Symbol	GHS08
Signal Word	Warning
Hazard Statements	H373-H412
Precautionary Statements	P273
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Faceshields;Gloves
Hazard Codes	Xn:Harmful;
Risk Phrases	R48/22;R52/53
Safety Phrases	S37-S61
RIDADR	UN 2811 6.1/PG 1
WGK Germany	2
RTECS	GN4830000
Packaging Group	II
Hazard Class	6.1(a)

Articles9

A chiral separation strategy for acidic drugs in capillary electrochromatography using both chlorinated and nonchlorinated polysaccharide-based selectors.

Electrophoresis 35(19) , 2807-18, (2014)

A generic chiral separation strategy for the analysis of acidic compounds in CEC is proposed in completion of an earlier defined strategy for nonacidic compounds. The screening step of this strategy u...

Single-step approach for fabrication of vancomycin-bonded silica monolith as chiral stationary phase.

J. Chromatogr. A. 1358 , 208-16, (2014)

A vancomycin-bonded silica monolithic column for capillary electrochromatography (CEC) was prepared by a single-step in situ sol-gel approach. This sol-gel process incorporates a synthetic sol-gel pre...

Toxicology and histopathology of some rodenticides and palatable food items combinations on the common mice Mus musculus var. albus in Egypt.

Commun. Agric. Appl. Biol. Sci. 68(4 Pt B) , 771-87, (2003)

In this study the palatability tests of certain food items as attractants in the poisoned-baits for the albino mouse Mus musculus var. albus showed that the food items of treacle, maize oil, dry or we...

Synonyms

UNII:UCD8XZW42P

3-(1-(4-Chlorophenyl)-3-oxobutyl)-4-hydroxy-2H-1-benzopyran-2-one (9CI)

MFCD00012094

2H-1-Benzopyran-2-one, 3-[1-(4-chlorophenyl)-3-oxobutyl]-4-hydroxy-

3-(a-Acetonyl-p-chlorobenzyl)-4-hydroxycoumarin

tomorin

3-[(1RS)-1-(4-chlorophenyl)-3-oxobutyl]-4-hydroxycoumarin

3-(a-p-Chlorophenyl-b-acetylethyl)-4-hydroxycoumarin

3-[1-(4-Chlorophenyl)-3-oxobutyl]-4-hydroxy-2H-1-benzopyran-2-one

Coumachlor

Geigy Rodenticide Exp.332

FAMARIN

rac-3-[(1R)-1-(4-chlorophenyl)-3-oxobutyl]-4-hydroxy-2H-1-benzopyran-2-one

3-[1-(4-Chlorophenyl)-3-oxobutyl]-4-hydroxy-2H-chromen-2-one

ratilan

P-CHLOROWARFARIN

cumachloor

kumachlor

(±)-3-(1-(p-Chlorophenyl)-3-oxobutyl)-4-hydroxycoumarin

EINECS 201-378-1

(±)-Coumachlor

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