CAS 76260-78-1|Substance P-methyl ester

Introduction:Basic information about CAS 76260-78-1|Substance P-methyl ester, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameSubstance P-methyl ester
CAS Number76260-78-1Molecular Weight1362.64000
Density1.41g/cm3Boiling Point/
Molecular FormulaC64H99N17O14SMelting Point/
MSDS/Flash Point/

Names

NameSubstance P-methyl ester
SynonymMore Synonyms

Substance P-methyl ester BiologicalActivity

DescriptionSubstance P, [Met-OMet11] is a selective SP-P agonist. Substance P, [Met-OMet11] also is an active peptide. Substance P, [Met-OMet11] can be used for various biochemical studies[1][2].
Related CatalogResearch Areas >>OthersSignaling Pathways >>Others >>Others
In VitroSubstance P, [Met-OMet11] (substance P Me ester) 在刺激流涎和回肠收缩方面的效力为 30%[1]。
References

[1]. M A Cascieri, et al. Biological activity of substance P methyl ester. Mol Pharmacol  

[2]. C M Lee, et al. Multiple tachykinin binding sites in peripheral tissues and in brain. Eur J Pharmacol. 1986 Nov 4;130(3):209-17.  

Chemical & Physical Properties

Density1.41g/cm3
Molecular FormulaC64H99N17O14S
Molecular Weight1362.64000
Exact Mass1361.73000
PSA525.14000
LogP4.18150
Index of Refraction1.653
InChIKeyCWWARWOPSKGELM-UHFFFAOYSA-N
SMILESCOC(=O)C(CCSC)NC(=O)C(CC(C)C)NC(=O)CNC(=O)C(Cc1ccccc1)NC(=O)C(Cc1ccccc1)NC(=O)C(CCC(N)=O)NC(=O)C(CCC(N)=O)NC(=O)C1CCCN1C(=O)C(CCCCN)NC(=O)C1CCCN1C(=O)C(N)CCCN=C(N)N

Safety Information

WGK Germany3

Synonyms

L-Arg-L-Pro-L-Lys-L-Pro-Gln-L-Gln-L-Phe-L-Phe-Gly-L-Leu-L-Met-OMe
SP methyl ester
SUBSTANCE P METHYL ESTER
Substance P,[Met-OMet11]
H-ARG-PRO-LYS-PRO-GLN-GLN-PHE-PHE-GLY-LEU-MET-OME
L-Arg-L-Pro-L-Lys-L-Pro-L-Glu(NH2)-L-Glu(NH2)-L-Phe-L-Phe-Gly-L-Leu-L-Met-OMe
Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-OMe,Substance P methyl ester
methylester-substance
substance P-O-methyl ester
ARG-PRO-LYS-PRO-GLN-GLN-PHE-PHE-GLY-LEU-MET-OME
[Met-OMe11]-substance P
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