CAS 108825-65-6|Lin28-IN-1632

Introduction：Basic information about CAS 108825-65-6|Lin28-IN-1632, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Lin28-IN-1632 BiologicalActivity
3. Chemical & Physical Properties
4. Safety Information
5. Customs
6. Synonyms

Common Name	Lin28-IN-1632
CAS Number	108825-65-6	Molecular Weight	281.31300
Density	1.28g/cm3	Boiling Point	/
Molecular Formula	C₁₅H₁₅N₅O	Melting Point	200ºC
MSDS	/	Flash Point	/

Names

Name	N-methyl-N-[3-(3-methyl-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)phenyl]acetamide
Synonym	More Synonyms

Lin28-IN-1632 BiologicalActivity

Description	Lin28-let-7 antagonist 1 (compound 1632) is a potent antagonist of Lin28/pre-let-7 interaction. Lin28-let-7 antagonist 1 inhibits Lin28A binding to pre-let-7a-2, with an IC50 of 8 μM. Lin28-let-7 antagonist 1 inhibits proliferation in human cancer cells[1].
Related Catalog	Research Areas >>CancerSignaling Pathways >>Others >>OthersResearch Areas >>Neurological Disease
References	[1]. Roos M, et al. A Small-Molecule Inhibitor of Lin28. ACS Chem Biol. 2016 Oct 21;11(10):2773-2781.

Chemical & Physical Properties

Density	1.28g/cm3
Melting Point	200ºC
Molecular Formula	C₁₅H₁₅N₅O
Molecular Weight	281.31300
Exact Mass	281.12800
PSA	63.39000
LogP	2.08240
Index of Refraction	1.665
InChIKey	WPAQLESUVYGUJZ-UHFFFAOYSA-N
SMILES	CC(=O)N(C)c1cccc(-c2ccc3nnc(C)n3n2)c1
Storage condition	-20°C

Safety Information

Hazard Codes	Xi: Irritant;
Safety Phrases	S24/25
HS Code	2933990090

Customs

HS Code	2933990090
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Synonyms

Acetamide,N-methyl-N-[3-(3-methyl-1,2,4-triazolo[4,3-b]pyridazin-6-yl)phenyl]

N-Methyl-N-(3-(3-methyl-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)phenyl)acetamide

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