CAS 89250-26-0|2-(Chloromethyl)-4-(4-Nitrophenyl)-1,3-Thiazole

Introduction：Basic information about CAS 89250-26-0|2-(Chloromethyl)-4-(4-Nitrophenyl)-1,3-Thiazole, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common Name2-(Chloromethyl)-4-(4-Nitrophenyl)-1,3-Thiazole
CAS Number89250-26-0Molecular Weight254.69
Density1.4±0.1 g/cm3Boiling Point406.2±30.0 °C at 760 mmHg
Molecular FormulaC10H7ClN2O2SMelting Point154.5ºC
MSDS/Flash Point199.5±24.6 °C

Names

Name2-(Chloromethyl)-4-(4-nitrophenyl)thiazole
SynonymMore Synonyms

BiologicalActivity

Description2-(Chloromethyl)-4-(4-nitrophenyl)thiazole (Compound APS) has anti-cancer activity in hepatocellular carcinoma (HCC) by repression of M2 polarization of Tumor-associated macrophages (TAMs). 2-(Chloromethyl)-4-(4-nitrophenyl)thiazole can be isolated from Astragalus propinquus Schischk[1].
Related CatalogResearch Areas >>CancerSignaling Pathways >>Others >>Others
References

[1]. Li C, et al. Astragalus polysacharin inhibits hepatocellular carcinoma-like phenotypes in a murine HCC model through repression of M2 polarization of tumour-associated macrophages. Pharm Biol. 2021 Dec;59(1):1533-1539.  

Chemical & Physical Properties

Density1.4±0.1 g/cm3
Boiling Point406.2±30.0 °C at 760 mmHg
Melting Point154.5ºC
Molecular FormulaC10H7ClN2O2S
Molecular Weight254.69
Flash Point199.5±24.6 °C
Exact Mass253.991669
PSA86.95000
LogP2.71
Vapour Pressure0.0±0.9 mmHg at 25°C
Index of Refraction1.638
InChIKeyLEBRGKZHLICZCZ-UHFFFAOYSA-N
SMILESO=[N+]([O-])c1ccc(-c2csc(CCl)n2)cc1

Safety Information

Hazard CodesXi
Risk Phrases34
Safety Phrases22-26-36/37/39-45
HS Code2932999099

Customs

HS Code2934100090
Summary2934100090 other compounds containing an unfused thiazole ring (whether or not hydrogenated) in the structure VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%

Synonyms

2-(chloromethyl)-4-(4-nitrophenyl)-1,3-thiazole
CAS 1177740-61-2|N-(2-(dimethylamino)ethyl)-N-(4-ethoxybenzo[d]thiazol-2-yl)-3-(phenylsulfonyl)propa
CAS 1215662-31-9|N-[2-(Dimethylamino)ethyl]-N-(4-fluoro-1,3-benzothiazol-2-YL)acetamide hydrochlorid
Recommended......
CAS 89-72-5|2-sec-Butylphenol CAS 89167-34-0|4-Chloro-3-iodo CAS 89694-46-2|(2-Chloro-5-met CAS 894-71-3|Nortriptyline Hyd CAS 89536-84-5|Boc-N-methyl-D- CAS 89536-85-6|Boc-DN-Me-Val-O CAS 898747-12-1|4-Methoxy-1H-i CAS 893566-31-9|3-Methoxy-4-me CAS 89028-37-5|BIS(1-BENZOTRIA CAS 893637-97-3|4'-CHLORO- CAS 89205-07-2|5-(4-methoxyphe CAS 898787-03-6|2,5-dimethoxyb CAS 89268-03-1|1-[(Chlorometho CAS 899822-97-0|3-Nitro-1-(4-o CAS 89007-51-2|2,6-dichloropip CAS 89464-26-6|TETRAHYDRO-2H-P CAS 89483-07-8|Boc-L-Cycloprop CAS 893745-85-2|4-(1-PIPERIDIN CAS 89001-53-6|p-Nitro-α CAS 89073-57-4|1,3-DIPROPYL-8-
Disclaimer

This site is a non-commercial website, not accept any sponsorship and advertising. The content is collated from the Internet, does not represent the position of this site, for personal reference only, please distinguish by yourself! The belongs to the original author.

Copyright © 2025 All Rights Reserved.

TOP