CAS 2439-99-8|Glyphosine

Introduction：Basic information about CAS 2439-99-8|Glyphosine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Chemical & Physical Properties
3. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
4. Safety Information
5. Customs
6. Articles6
7. Synonyms

Common Name	Glyphosine
CAS Number	2439-99-8	Molecular Weight	263.080
Density	2.0±0.1 g/cm3	Boiling Point	668.4±65.0 °C at 760 mmHg
Molecular Formula	C₄H₁₁NO₈P₂	Melting Point	263°C
MSDS	ChineseUSA	Flash Point	358.0±34.3 °C
Symbol	GHS05	Signal Word	Danger

Names

Name	glyphosine
Synonym	More Synonyms

Chemical & Physical Properties

Density	2.0±0.1 g/cm3
Boiling Point	668.4±65.0 °C at 760 mmHg
Melting Point	263°C
Molecular Formula	C₄H₁₁NO₈P₂
Molecular Weight	263.080
Flash Point	358.0±34.3 °C
Exact Mass	262.996002
PSA	175.22000
LogP	-2.89
Vapour Pressure	0.0±4.4 mmHg at 25°C
Index of Refraction	1.594
InChIKey	OXHDYFKENBXUEM-UHFFFAOYSA-N
SMILES	O=C(O)CN(CP(=O)(O)O)CP(=O)(O)O

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: MB9120000

CHEMICAL NAME :: Glycine, N,N-bis(phosphonomethyl)-

CAS REGISTRY NUMBER :: 2439-99-8

LAST UPDATED :: 199701

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C4-H11-N-O8-P2

MOLECULAR WEIGHT :: 263.10

WISWESSER LINE NOTATION :: QPQO&1N1VQ1PQQO

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 3925 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 85ARAE "Agricultural Chemicals," Thomson, W.T., 4 vols., Fresno, CA, Thomson Publications, 1976/77 revision Volume(issue)/page/year: 3,60,1976/1977 ** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1920 mg/kg/24D-C

TOXIC EFFECTS :: Liver - changes in liver weight Endocrine - changes in thymus weight Immunological Including Allergic - decrease in humoral immune response

REFERENCE :: TXCYAC Toxicology. (Elsevier Scientific Pub. Ireland, Ltd., POB 85, Limerick, Ireland) V.1- 1973- Volume(issue)/page/year: 30,103,1984

Safety Information

Symbol	GHS05
Signal Word	Danger
Hazard Statements	H318
Precautionary Statements	P280-P305 + P351 + P338
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xi:Irritant;
Risk Phrases	R41
Safety Phrases	S26-S2
RIDADR	UN 3261 8/PG 3
WGK Germany	1
RTECS	MB9120000
Packaging Group	III
Hazard Class	8.0
HS Code	2931900042

Customs

HS Code	2931900042
Summary	2931900042 2-(bis(phosphonomethyl)amino)acetic acid。supervision conditions:s(import or export registration certificate for pesticides)。VAT:17.0%。tax rebate rate:9.0%。MFN tarrif:6.5%。general tariff:30.0%

Articles6

Structure-based selection of small molecules to alter allele-specific MHC class II antigen presentation.

J. Immunol. 11th ed., 187 , 5921-5930, (2011)

Class II major histocompatibility molecules are the primary susceptibility locus for many autoimmune disorders, including type 1 diabetes. Human DQ8 and I-A(g7), in the NOD mouse model of spontaneous ...

Binding of phosphonate chelating agents and pyrophosphate to apotransferrin.

Biochemistry 30(28) , 6930-6, (1991)

Difference ultraviolet spectroscopy has been used to monitor the binding of a series of phosphonate ligands to human apotransferrin. The ligands consist of pyrophosphate as well as the phosphonic acid...

Synthesis, characterization, and in vitro antitumor activity of osteotropic diam(m)ineplatinum(II) complexes bearing a N,N-bis(phosphonomethyl)glycine ligand.

J. Med. Chem. 46(23) , 4946-51, (2003)

A series of osteotropic (bone-seeking) [(bis(phosphonomethyl)amino-kappaN)acetato-kappaO(2-)]platinum(II) complexes attached to diammine, ethane-1,2-diamine, cis-R,S-cyclohexane-1,2-diamine, trans-S,S...

Synonyms

Glycine-N,N-bis(methylenephosphonic Acid)

N,N-di(phosphonomethyl) iminoacetic acid

N,N-bis(phosphonomethyl)aminoacetic acid

<<(carboxymethyl)imino>dimethylene>bisphosphonic acid

EINECS 219-468-4

Glyphosine [ANSI]

2-[bis(phosphonomethyl)amino]acetic acid

Glycine,N,N-bis(phosphonomethyl)

Glycine, N,N-bis(phosphonomethyl)-

N,N-bis-(phosphonomethyl)-glycine

Polaris

Glyphosphine

bis-phosphonomethyl glycine

MFCD00056670

2-(Bis(phosphonomethyl)amino)acetic acid

N,N-Bis(phosphonomethyl)glycine

nitriloacetatodimethylenephosphonic acid

N-Carboxymethyl-N,N-bis(methylenephosphonic Acid)amine

Caswell No. 471A

Glyphosine

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