CAS 105931-58-6|N6-Methyl-dA phosphoramidite

Introduction:Basic information about CAS 105931-58-6|N6-Methyl-dA phosphoramidite, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameN6-Methyl-dA phosphoramidite
CAS Number105931-58-6Molecular Weight751.853
Density/Boiling Point862.0±75.0 °C at 760 mmHg
Molecular FormulaC41H50N7O5PMelting Point/
MSDS/Flash Point475.1±37.1 °C

Names

Name5'-o-(4,4'-dimethoxytrityl)-n6-methyl-2'-deoxyadenosine, 3'-[(2-cyanoethyl)-(n,n-diisopropyl)]phosphoramidite
SynonymMore Synonyms

N6-Methyl-dA phosphoramidite BiologicalActivity

DescriptionN6-Methyl-dA phosphoramidite can be used in the synthesis of oligodeoxyribonucleotides[1].
Related CatalogSignaling Pathways >>Cell Cycle/DNA Damage >>DNA/RNA SynthesisSignaling Pathways >>Cell Cycle/DNA Damage >>Nucleoside Antimetabolite/AnalogResearch Areas >>Others
References

[1]. Li D, et, al. Exocyclic carbons adjacent to the N6 of adenine are targets for oxidation by the Escherichia coli adaptive response protein AlkB. J Am Chem Soc. 2012 May 30;134(21):8896-901.

Chemical & Physical Properties

Boiling Point862.0±75.0 °C at 760 mmHg
Molecular FormulaC41H50N7O5P
Molecular Weight751.853
Flash Point475.1±37.1 °C
Exact Mass751.361084
PSA142.40000
LogP8.48
Vapour Pressure0.0±3.3 mmHg at 25°C
InChIKeyPTWRBAYAPDVZGR-JNTXQERPSA-N
SMILESCNc1ncnc2c1ncn2C1CC(OP(OCCC#N)N(C(C)C)C(C)C)C(COC(c2ccccc2)(c2ccc(OC)cc2)c2ccc(OC)cc2)O1
Storage condition2-8℃

Synonyms

Adenosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-3'-O-[[bis(1-methylethyl)amino](2-cyanoethyl)phosphino]-2'-deoxy-N-methyl-
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-[(2-cyanoethyl)(diisopropylamino)phosphino]-2'-deoxy-N-methyladenosine
N6-METHYL-DA CEP
2'-Deoxy-5'-O-DMT-N6-methyladenosine 3'-CE phosphoramidite
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