Introduction:Basic information about CAS 105931-58-6|N6-Methyl-dA phosphoramidite, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | N6-Methyl-dA phosphoramidite |
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| CAS Number | 105931-58-6 | Molecular Weight | 751.853 |
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| Density | / | Boiling Point | 862.0±75.0 °C at 760 mmHg |
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| Molecular Formula | C41H50N7O5P | Melting Point | / |
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| MSDS | / | Flash Point | 475.1±37.1 °C |
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Names
| Name | 5'-o-(4,4'-dimethoxytrityl)-n6-methyl-2'-deoxyadenosine, 3'-[(2-cyanoethyl)-(n,n-diisopropyl)]phosphoramidite |
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| Synonym | More Synonyms |
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N6-Methyl-dA phosphoramidite BiologicalActivity
| Description | N6-Methyl-dA phosphoramidite can be used in the synthesis of oligodeoxyribonucleotides[1]. |
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| Related Catalog | Signaling Pathways >>Cell Cycle/DNA Damage >>DNA/RNA SynthesisSignaling Pathways >>Cell Cycle/DNA Damage >>Nucleoside Antimetabolite/AnalogResearch Areas >>Others |
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| References | [1]. Li D, et, al. Exocyclic carbons adjacent to the N6 of adenine are targets for oxidation by the Escherichia coli adaptive response protein AlkB. J Am Chem Soc. 2012 May 30;134(21):8896-901. |
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Chemical & Physical Properties
| Boiling Point | 862.0±75.0 °C at 760 mmHg |
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| Molecular Formula | C41H50N7O5P |
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| Molecular Weight | 751.853 |
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| Flash Point | 475.1±37.1 °C |
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| Exact Mass | 751.361084 |
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| PSA | 142.40000 |
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| LogP | 8.48 |
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| Vapour Pressure | 0.0±3.3 mmHg at 25°C |
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| InChIKey | PTWRBAYAPDVZGR-JNTXQERPSA-N |
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| SMILES | CNc1ncnc2c1ncn2C1CC(OP(OCCC#N)N(C(C)C)C(C)C)C(COC(c2ccccc2)(c2ccc(OC)cc2)c2ccc(OC)cc2)O1 |
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| Storage condition | 2-8℃ |
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Synonyms
| Adenosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-3'-O-[[bis(1-methylethyl)amino](2-cyanoethyl)phosphino]-2'-deoxy-N-methyl- |
| 5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-[(2-cyanoethyl)(diisopropylamino)phosphino]-2'-deoxy-N-methyladenosine |
| N6-METHYL-DA CEP |
| 2'-Deoxy-5'-O-DMT-N6-methyladenosine 3'-CE phosphoramidite |