Introduction：Basic information about CAS 10212-19-8|2'-Chloro-2'-deoxycytidine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 2'-Chloro-2'-deoxycytidine |
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| CAS Number | 10212-19-8 | Molecular Weight | 261.66 |
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| Density | 1.9±0.1 g/cm3 | Boiling Point | 551.3±60.0 °C at 760 mmHg |
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| Molecular Formula | C9H12ClN3O4 | Melting Point | / |
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| MSDS | / | Flash Point | 287.2±32.9 °C |
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Names
| Name | 4-amino-1-[(2R,3R,4R,5R)-3-chloro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one |
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| Synonym | More Synonyms |
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2'-Chloro-2'-deoxycytidine BiologicalActivity
| Description | 2-Chloro-2'-deoxycytidine is a cytidine nucleoside analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities[1]. |
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| Related Catalog | Signaling Pathways >>Cell Cycle/DNA Damage >>Nucleoside Antimetabolite/AnalogResearch Areas >>Others |
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| References | [1]. Gowher H, et al. Mechanism of inhibition of DNA methyltransferases by cytidine analogs in cancer therapy. Cancer Biol Ther. 2004 Nov;3(11):1062-8. |
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Chemical & Physical Properties
| Density | 1.9±0.1 g/cm3 |
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| Boiling Point | 551.3±60.0 °C at 760 mmHg |
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| Molecular Formula | C9H12ClN3O4 |
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| Molecular Weight | 261.66 |
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| Flash Point | 287.2±32.9 °C |
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| Exact Mass | 261.051636 |
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| PSA | 110.60000 |
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| LogP | -1.43 |
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| Vapour Pressure | 0.0±3.4 mmHg at 25°C |
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| Index of Refraction | 1.736 |
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| InChIKey | LOZPBORRQPATRO-XVFCMESISA-N |
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| SMILES | Nc1ccn(C2OC(CO)C(O)C2Cl)c(=O)n1 |
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Synonyms
| Cytidine,2'-chloro-2'-deoxy-(8CI,9CI) |
| 2'-Chlor-2'-deoxycytidin |
| 2'-Chloro-2'-deoxycytidine |
| 2'-Chlor-2'-desoxy-cytidin |
| Cytidine, 2'-chloro-2'-deoxy- |
| 2'-chloro-2'-deoxy-cytidine |
| 2'-Deoxy-2'-chlorocytidine |
