CAS 506-32-1|Arachidonic acid
Introduction：Basic information about CAS 506-32-1|Arachidonic acid, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Arachidonic acid | ||
|---|---|---|---|
| CAS Number | 506-32-1 | Molecular Weight | 304.467 |
| Density | 0.9±0.1 g/cm3 | Boiling Point | 407.5±0.0 °C at 760 mmHg |
| Molecular Formula | C20H32O2 | Melting Point | −49 °C(lit.) |
| MSDS | ChineseUSA | Flash Point | 336.3±18.0 °C |
Names
| Name | arachidonic acid |
|---|---|
| Synonym | More Synonyms |
Arachidonic acid BiologicalActivity
| Description | Arachidonic acid is an essential fatty acid and a major constituent of biomembranes. |
|---|---|
| Related Catalog | Natural Products >>Acids and AldehydesResearch Areas >>Inflammation/Immunology |
| Target | Human Endogenous Metabolite |
| In Vivo | Arachidonic acid (ARA) is converted into various lipid mediators, such as prostaglandin E2 (PGE2), which is involved in the development of rheumatoid arthritis (RA)[1]. |
| References | [1]. Tateishi N, et al. Dietary supplementation with arachidonic acid increases arachidonic acid content in paw, but does not affect arthritis severity or prostaglandin E2 content in rat adjuvant-induced arthritis model. Lipids Health Dis. 2015 Jan 16;14:3. |
Chemical & Physical Properties
| Density | 0.9±0.1 g/cm3 |
|---|---|
| Boiling Point | 407.5±0.0 °C at 760 mmHg |
| Melting Point | −49 °C(lit.) |
| Molecular Formula | C20H32O2 |
| Molecular Weight | 304.467 |
| Flash Point | 336.3±18.0 °C |
| Exact Mass | 304.240234 |
| PSA | 37.30000 |
| LogP | 6.91 |
| Vapour Pressure | 0.0±2.0 mmHg at 25°C |
| Index of Refraction | 1.501 |
| InChIKey | YZXBAPSDXZZRGB-DOFZRALJSA-N |
| SMILES | CCCCCC=CCC=CCC=CCC=CCCCC(=O)O |
| Water Solubility | PRACTICALLY INSOLUBLE |
Toxicological Information
CHEMICAL IDENTIFICATION |
ACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 39200 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- DOSE :
- 80 ug/kg
- SEX/DURATION :
- female 1 day(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Maternal Effects - uterus, cervix, vagina
MUTATION DATA - TYPE OF TEST :
- Sister chromatid exchange
- TEST SYSTEM :
- Rodent - hamster Ovary
- DOSE/DURATION :
- 320 umol/L
- REFERENCE :
- PAACA3 Proceedings of the American Association for Cancer Research. (Waverly Press, 428 E. Preston St., Baltimore, MD 21202) V.1- 1954- Volume(issue)/page/year: 27,95,1986 *** REVIEWS *** TOXICOLOGY REVIEW JACTDZ Journal of the American College of Toxicology. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1-12, 1982-1993. Discontinued. Volume(issue)/page/year: 12,481,1993 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - T1132 No. of Facilities: 27 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 79 (estimated) No. of Female Employees: 60 (estimated)
- TYPE OF TEST :
- Sister chromatid exchange
- TEST SYSTEM :
- Rodent - hamster Ovary
- DOSE/DURATION :
- 320 umol/L
- REFERENCE :
- PAACA3 Proceedings of the American Association for Cancer Research. (Waverly Press, 428 E. Preston St., Baltimore, MD 21202) V.1- 1954- Volume(issue)/page/year: 27,95,1986 *** REVIEWS *** TOXICOLOGY REVIEW JACTDZ Journal of the American College of Toxicology. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1-12, 1982-1993. Discontinued. Volume(issue)/page/year: 12,481,1993 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - T1132 No. of Facilities: 27 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 79 (estimated) No. of Female Employees: 60 (estimated)
Safety Information
| Personal Protective Equipment | Eyeshields;Faceshields;Gloves;half-mask respirator (US);multi-purpose combination respirator cartridge (US) |
|---|---|
| Hazard Codes | F |
| Risk Phrases | R19 |
| Safety Phrases | S24/25 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| RTECS | CE6675000 |
| Packaging Group | I; II; III |
| Hazard Class | 6.1 |
| HS Code | 2916190090 |
Customs
| HS Code | 2916190090 |
|---|---|
| Summary | 2916190090 unsaturated acyclic monocarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives。supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward)。VAT:17.0%。tax rebate rate:9.0%。MFN tariff:6.5%。general tariff:30.0% |
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Synonyms
| (5Z,8Z,11Z,14Z)-Icosa-5,8,11,14-tetraenoic acid |
| AA |
| Immunocytophyte |
| eicosatetraenoic acid |
| MFCD00004417 |
| PUFA 20:4n-6 |
| ARACHIDONIC ACID(RG) |
| 5,8,11,14-Icosatetraenoic Acid |
| Arachidonic acid |
| Hydrazinecarboselenoamide |
| ARA |
| 5,8,11,14-Eicosatetraenoic Acid |
| (5Z,8Z,11Z,14Z)-5,8,11,14-Icosatetraenoic acid |
| C20:4 (cis-5,8,11,14) |
| 20:4n-6 |
| 5,8,11,14-all-cis-Eicosatetraenoic acid |
| 5,8,11,14-Eicosatetraenoic acid, (all-Z)- |
| 5,8,11,14-Eicosatetraenoic acid, (5Z,8Z,11Z,14Z)- |
| Arachidonate |
| (5Z,8Z,11Z,14Z)-5,8,11,14-Eicosatetraenoic acid |
| Arachidonic |
| EINECS 208-033-4 |
| (all-Z)-5,8,11,14-Eicosatetraenoic acid |
