CAS 2935-44-6|2,5-Hexanediol
Introduction：Basic information about CAS 2935-44-6|2,5-Hexanediol, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 2,5-Hexanediol | ||
|---|---|---|---|
| CAS Number | 2935-44-6 | Molecular Weight | 118.174 |
| Density | 1.0±0.1 g/cm3 | Boiling Point | 213.4±8.0 °C at 760 mmHg |
| Molecular Formula | C6H14O2 | Melting Point | / |
| MSDS | ChineseUSA | Flash Point | 101.7±0.0 °C |
| Symbol | GHS07 | Signal Word | Warning |
Names
| Name | hexane-2,5-diol |
|---|---|
| Synonym | More Synonyms |
Chemical & Physical Properties
| Density | 1.0±0.1 g/cm3 |
|---|---|
| Boiling Point | 213.4±8.0 °C at 760 mmHg |
| Molecular Formula | C6H14O2 |
| Molecular Weight | 118.174 |
| Flash Point | 101.7±0.0 °C |
| Exact Mass | 118.099380 |
| PSA | 40.46000 |
| LogP | -0.33 |
| Vapour Pressure | 0.0±0.9 mmHg at 25°C |
| Index of Refraction | 1.445 |
| InChIKey | OHMBHFSEKCCCBW-UHFFFAOYSA-N |
| SMILES | CC(O)CCC(C)O |
| Storage condition | 2-8°C |
Toxicological Information
CHEMICAL IDENTIFICATION |
ACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 2 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JAFCAU Journal of Agricultural and Food Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB 57136, West End Stn., Washington, DC 20037) V.1- 1953- Volume(issue)/page/year: 23,418,1975
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 4846 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JAPMA8 Journal of the American Pharmaceutical Association, Scientific Edition. (Washington, DC) V.29-49, 1940-60. For publisher information, see JPMSAE. Volume(issue)/page/year: 45,669,1956
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 16300 uL/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JIHTAB Journal of Industrial Hygiene and Toxicology. (Cambridge, MA) V.18-31, 1936-49. For publisher information, see AEHLAU. Volume(issue)/page/year: 30,63,1948 ** OTHER MULTIPLE DOSE TOXICITY DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 29400 mg/kg/11W-I
- TOXIC EFFECTS :
- Autonomic Nervous System - other (direct) parasympathomimetic
- REFERENCE :
- EESADV Ecotoxicology and Environmental Safety. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1977- Volume(issue)/page/year: 3,204,1979
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 35 gm/kg/5W-C
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Eye) - retinal changes (pigmentary depositions, retinitis, other) Autonomic Nervous System - other (direct) parasympathomimetic
- REFERENCE :
- ARTODN Archives of Toxicology. (Springer-Verlag, Heidelberger Pl. 3, D-1000 Berlin 33, Fed. Rep. Ger.) V.32- 1974- Volume(issue)/page/year: 67,277,1993
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 7 gm/kg/7D-I
- TOXIC EFFECTS :
- Endocrine - other changes Endocrine - changes in thymus weight
- REFERENCE :
- IJEBA6 Indian Journal of Experimental Biology. (Publications & Information Directorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963- Volume(issue)/page/year: 24,371,1986
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 22423 mg/kg/7D-I
- TOXIC EFFECTS :
- Endocrine - changes in adrenal weight Endocrine - changes in thymus weight Immunological Including Allergic - decrease in humoral immune response
- REFERENCE :
- ENVRAL Environmental Research. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1967- Volume(issue)/page/year: 36,14,1985
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Bird - chicken
- DOSE/DURATION :
- 9 gm/kg/90D-I
- TOXIC EFFECTS :
- Spinal Cord - demyelination Spinal Cord - other degenerative changes Behavioral - ataxia
- REFERENCE :
- TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 62,369,1982
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Bird - chicken
- DOSE/DURATION :
- 18 gm/kg/90D-I
- TOXIC EFFECTS :
- Spinal Cord - other degenerative changes Peripheral Nerve and Sensation - spastic paralysis with or without sensory change Peripheral Nerve and Sensation - structural change in nerve or sheath
- REFERENCE :
- TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 62,369,1982
Safety Information
| Symbol | GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H302-H315-H319-H335 |
| Precautionary Statements | P261-P305 + P351 + P338 |
| Personal Protective Equipment | Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter |
| Hazard Codes | Xn |
| Risk Phrases | R22:Harmful if swallowed. R36/37/38:Irritating to eyes, respiratory system and skin . |
| Safety Phrases | S26-S36-S37/39 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| RTECS | MO2275000 |
| HS Code | 2905399090 |
Customs
| HS Code | 2905399090 |
|---|---|
| Summary | 2905399090 other diols。supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward)。VAT:17.0%。tax rebate rate:9.0%。MFN tariff:5.5%。general tariff:30.0% |
Articles25
More Articles| Pattern of neurotoxicity of n-hexane, methyl n-butyl ketone, 2,5-hexanediol, and 2,5-hexanedione alone and in combination with O-ethyl O-4-nitrophenyl phenylphosphonothioate in hens. J. Toxicol. Environ. Health A 16(1) , 85-100, (1985) This investigation was designed to study the neurotoxicity produced in hens by the aliphatic hexacarbons n-hexane, methyl n-butyl ketone (MnBK), 2,5-hexanediol (2,5-HDOH), and 2,5-hexanedione (2,5-HD)... | |
| The antimycotic activity in vitro of five diols. Sabouraudia 18(4) , 287-93, (1980) The antimycotic activity of ethane-1,2-diol, propane-1,2-diol, butane-1,3-diol, pentane-1,5-diol, and hexane-2,5-diol in vitro against Pityrosporum orbiculare, Candida albicans, Trichophyton rubrum, T... | |
| [Effects of 2,5-hexanediol, 2,4-pentanedione, acetone and 2-heptanone on the secretory responsiveness of the sweat glands in rats (author's transl)]. Sangyo. Igaku. 22(6) , 494-5, (1980) |
Synonyms
| 2,5-Hexanediol 3 M |
| Diisopropanol |
| (2R,5R)-2.5-hexanediol |
| 2,5-Hexanediol |
| 2,5-Hexylene glycol |
| 2,5-Dihydroxyhexane |
| Hexane-2,5-diol |
| dl/meso-2,5-hexanediol |
| MFCD00004557 |
| 2,5-hexandiol |
| EINECS 220-910-3 |
| 2,4-DINITROTOLUENE-6-SULFONIC ACID |
