Introduction：Basic information about CAS 76494-51-4|Ligustrazine Hydrochloride, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Ligustrazine Hydrochloride |
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| CAS Number | 76494-51-4 | Molecular Weight | 136.19 |
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| Density | / | Boiling Point | 192.7ºC at 760mmHg |
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| Molecular Formula | C8H12N2 | Melting Point | / |
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| MSDS | / | Flash Point | 71.6ºC |
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Names
| Name | 2,3,5,6-tetramethylpyrazine,hydrochloride |
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| Synonym | More Synonyms |
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Ligustrazine Hydrochloride BiologicalActivity
| Description | Ligustrazine (hydrochloride) is a natural product.IC50 value:Target:In vitro: Ligustrazine hydrochloride displayed a protection effect on injured ECV304 cells, NOS and NO formation were significantly increased compared with the model group [1].In vivo: |
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| Related Catalog | Signaling Pathways >>Others >>OthersNatural Products >>AlkaloidResearch Areas >>Others |
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| References | [1]. Xu D, et al. Protective effect of ligustrazine hydrochloride on homocysteine-injured ECV304 cells. Zhongguo Zhong Yao Za Zhi. 2012 Jun;37(12):1836-9. [2]. Wang Q, et al. Brain microdialysate, CSF and plasma pharmacokinetics of ligustrazine hydrochloride in rats after intranasal and intravenous administration. Biopharm Drug Dispos. 2013 Oct;34(7):417-22. |
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Chemical & Physical Properties
| Boiling Point | 192.7ºC at 760mmHg |
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| Molecular Formula | C8H12N2 |
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| Molecular Weight | 136.19 |
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| Flash Point | 71.6ºC |
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| PSA | 25.78000 |
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| LogP | 2.51220 |
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| InChIKey | RQKFOGXUTRDQPB-UHFFFAOYSA-N |
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| SMILES | Cc1nc(C)c(C)nc1C.Cl |
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Safety Information
| Hazard Codes | Xi |
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| HS Code | 2942000000 |
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Customs
| HS Code | 2933990090 |
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| Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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Synonyms
| Pyrazine, tetramethyl-, hydrochloride |
| Pyrazine, 2,3,5,6-tetramethyl-, hydrochloride (1:1) |
| tetramethylpyrazine hydrochloride |
| T6N DNJ B1 C1 E1 F1 &&HCl |
| Ligustrazine hydrochloride |
| 2,3,5,6-tetramethylpyrazine hydrochloride |
| Tetramethylpyrazine hydrochloride (1:1) |
| Ligustrazine HCl,hydrochloride |
| Ligustrazine Hydrochloride |
