CAS 23249-97-0|Procodazole

Introduction：Basic information about CAS 23249-97-0|Procodazole, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Procodazole BiologicalActivity
3. Chemical & Physical Properties
4. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
5. Safety Information
6. Preparation
7. Customs
8. Synonyms

Common Name	Procodazole
CAS Number	23249-97-0	Molecular Weight	190.19900
Density	1.367 g/cm3	Boiling Point	497.9ºC at 760 mmHg
Molecular Formula	C₁₀H₁₀N₂O₂	Melting Point	229-231 °C (dec.)(lit.)
MSDS	/	Flash Point	254.9ºC

Names

Name	3-(1H-benzimidazol-2-yl)propanoic acid
Synonym	More Synonyms

Procodazole BiologicalActivity

Description	Procodazole is a non-specific active immunoprotective agent against viral and bacterial infections, used as a potentiator.
Related Catalog	Signaling Pathways >>Anti-infection >>BacterialResearch Areas >>Infection

Chemical & Physical Properties

Density	1.367 g/cm3
Boiling Point	497.9ºC at 760 mmHg
Melting Point	229-231 °C (dec.)(lit.)
Molecular Formula	C₁₀H₁₀N₂O₂
Molecular Weight	190.19900
Flash Point	254.9ºC
Exact Mass	190.07400
PSA	65.98000
LogP	1.58010
Vapour Pressure	9.84E-11mmHg at 25°C
InChIKey	XYWJNTOURDMTPI-UHFFFAOYSA-N
SMILES	O=C(O)CCc1nc2ccccc2[nH]1
Storage condition	2-8℃

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UE7480000

CHEMICAL NAME :: Propionic acid, 2-(2-benzimidazolyl)-

CAS REGISTRY NUMBER :: 23249-97-0

BEILSTEIN REFERENCE NO. :: 0156920

LAST UPDATED :: 199612

DATA ITEMS CITED :: 6

MOLECULAR FORMULA :: C10-H10-N2-O2

MOLECULAR WEIGHT :: 190.22

WISWESSER LINE NOTATION :: T56 BM DNJ C2VQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1700 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year: 2,191,1977

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 180 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year: 2,191,1977

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 2 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year: 2,191,1977

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1100 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year: 2,191,1977

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 390 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year: 2,191,1977

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1800 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year: 2,191,1977

Safety Information

Hazard Codes	Xn: Harmful;Xi: Irritant;
Risk Phrases	R20/21/22
Safety Phrases	S26-S37/39
WGK Germany	3
RTECS	UE7480000
HS Code	2933990090

Preparation

Customs

HS Code	2933990090
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Synonyms

3-(1H-benzo[d]imidazol-2-yl)propanoic acid

Procodazol

Procodazole

3-(1H-benzimidazol-2-yl)propanoic carboxylic acid

2-Benzimidazolepropionic acid

Propazole

2-benzimidazole propionic acid

1H-benzimidazole-2-propanoic acid

3-(1H-benzo-imidazol-2-yl)propionic acid

Procodazole [INN]

MFCD00041215

Propazol

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