CAS 93-60-7|Methyl nicotinate
Introduction：Basic information about CAS 93-60-7|Methyl nicotinate, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Methyl nicotinate | ||
|---|---|---|---|
| CAS Number | 93-60-7 | Molecular Weight | 137.136 |
| Density | 1.1±0.1 g/cm3 | Boiling Point | 209.0±0.0 °C at 760 mmHg |
| Molecular Formula | C7H7NO2 | Melting Point | 42-44 °C(lit.) |
| MSDS | ChineseUSA | Flash Point | 95.6±0.0 °C |
| Symbol | GHS07 | Signal Word | Warning |
Names
| Name | Methyl nicotinate |
|---|---|
| Synonym | More Synonyms |
Methyl nicotinate BiologicalActivity
| Description | Methyl nicotinate, the methyl ester of Niacin found in alcoholic beverages, that is used as an active ingredient as a rubefacient in over-the-counter topical preparations indicated for muscle and joint pain[1]. |
|---|---|
| Related Catalog | Signaling Pathways >>Others >>OthersResearch Areas >>Inflammation/Immunology |
| References | [1]. L. Johnston, et al. Muscle and joint pain: topical anti-inflammatories and analgesics: therapeutic. Professional Nursing Today, Volume 17, Issue 1, Jan 2013, p. 4-5. |
Chemical & Physical Properties
| Density | 1.1±0.1 g/cm3 |
|---|---|
| Boiling Point | 209.0±0.0 °C at 760 mmHg |
| Melting Point | 42-44 °C(lit.) |
| Molecular Formula | C7H7NO2 |
| Molecular Weight | 137.136 |
| Flash Point | 95.6±0.0 °C |
| Exact Mass | 137.047684 |
| PSA | 39.19000 |
| LogP | 0.88 |
| Vapour Pressure | 0.2±0.4 mmHg at 25°C |
| Index of Refraction | 1.511 |
| InChIKey | YNBADRVTZLEFNH-UHFFFAOYSA-N |
| SMILES | COC(=O)c1cccnc1 |
| Water Solubility | NEGLIGIBLE |
Toxicological Information
CHEMICAL IDENTIFICATION |
ACUTE TOXICITY DATA - TYPE OF TEST :
- LD - Lethal dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >1 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 85IXA4 "Structure et Activite Pharmacodyanmique des Medicaments du Systeme Nerveux Vegetatif," Bovet, D., and F. Bovet-Nitti, New York, S. Karger, 1948 Volume(issue)/page/year: -,428,1948
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Parenteral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 2 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- CBCCT* "Summary Tables of Biological Tests," National Research Council Chemical-Biological Coordination Center. (National Academy of Science Library, 2101 Constitution Ave., NW, Washington, DC 20418) Volume(issue)/page/year: 7,691,1955 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 80460 No. of Facilities: 100 (estimated) No. of Industries: 3 No. of Occupations: 7 No. of Employees: 2857 (estimated)
Safety Information
| Symbol | GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H315-H319-H335 |
| Precautionary Statements | P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xi:Irritant |
| Risk Phrases | R36/38 |
| Safety Phrases | S26-S36-S37/39 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| RTECS | QT1925000 |
| HS Code | 2936290090 |
Customs
| HS Code | 2933399090 |
|---|---|
| Summary | 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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Synonyms
| EINECS 202-261-8 |
| NIACIN METHYL ESTER |
| Methyl nictinate |
| Methylpyridin-3-carboxylat |
| 3-methoxycarbonylpyridine |
| nicotinic acid methyl ester |
| methylnicotinicacid |
| 3-pyridinecarboxylic acid methyl ester |
| MFCD00006388 |
| 3-Pyridinecarboxylic acid, methyl ester |
| methyl 3-nicotinate |
| Methyl nicotinate |
| Nikomet |
| FEMA 3709 |
| pyridine-3-carboxylic acid methyl ester |
| Nicometh |
| methyl 3-pyridinecarboxylate |
