CAS 23062-24-0|EURYCOMALACTONE(P)

Introduction：Basic information about CAS 23062-24-0|EURYCOMALACTONE(P), including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. EURYCOMALACTONE(P) BiologicalActivity
3. Chemical & Physical Properties
4. Safety Information
5. Synonyms

Common Name	EURYCOMALACTONE(P)
CAS Number	23062-24-0	Molecular Weight	348.390
Density	1.3±0.1 g/cm3	Boiling Point	588.1±50.0 °C at 760 mmHg
Molecular Formula	C₁₉H₂₄O₆	Melting Point	268-270 °C
MSDS	/	Flash Point	213.1±23.6 °C

Names

Name	Eurycomalactone
Synonym	More Synonyms

EURYCOMALACTONE(P) BiologicalActivity

Description	Eurycomalactone is a natural product found in Eurycoma longifolia Jack., acts as a potent NF-κB inhibitor, with an IC50 of 0.5 μM. Eurycomalactone inhibits protein synthesis, depletes cyclin D1, but does not affect TNFα-induced degradation of IκBα or the phosphorylation of IKKα/β and IκBα[1].
Related Catalog	Research Areas >>Others
Target	IC50: 0.5 μM (NF-κB)[1]
References	[1]. Malainer C, et al. Eurycomalactone Inhibits Expression of Endothelial Adhesion Molecules at a Post-Transcriptional Level. J Nat Prod. 2017 Dec 22;80(12):3186-3193.

Chemical & Physical Properties

Density	1.3±0.1 g/cm3
Boiling Point	588.1±50.0 °C at 760 mmHg
Melting Point	268-270 °C
Molecular Formula	C₁₉H₂₄O₆
Molecular Weight	348.390
Flash Point	213.1±23.6 °C
Exact Mass	348.157288
PSA	100.90000
LogP	-0.43
Vapour Pressure	0.0±3.7 mmHg at 25°C
Index of Refraction	1.576
InChIKey	OGHYZHNTIINXEO-MGBQOKOWSA-N
SMILES	CC1=CC(=O)C(O)C2(C)C1CC(=O)C1(C)C3C(=O)OC(C3C)C(O)C12

Safety Information

Hazard Codes	Xi

Synonyms

2,5-Methanonaphth[1,2-d]oxepin-4,6,10(2H)-trione, 1,5,5a,7,7a,11,11a,11b-octahydro-1,11-dihydroxy-5a,8,11a,12-tetramethyl-, (1R,2R,5S,5aR,7aS,11S,11aS,11bR,12R)-

(1S,2R,5S,9S,10S,11R,12R,13R,16R)-9,12-Dihydroxy-2,6,10,16-tetramethyl-14-oxatetracyclo[11.2.1.0.0]hexadec-6-ene-3,8,15-trione

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