Introduction：Basic information about CAS 80433-71-2|Calcium Levofolinate, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Calcium Levofolinate |
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| CAS Number | 80433-71-2 | Molecular Weight | 511.501 |
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| Density | / | Boiling Point | / |
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| Molecular Formula | C20H21CaN7O7 | Melting Point | 240-250ºC |
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| MSDS | / | Flash Point | / |
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Names
| Name | calcium,(2S)-2-[[4-[[(6S)-2-amino-5-formyl-4-oxo-1,6,7,8-tetrahydropteridin-6-yl]methylamino]benzoyl]amino]pentanedioate |
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| Synonym | More Synonyms |
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Calcium Levofolinate BiologicalActivity
| Description | Levoleucovorin calcium is the calcium salt of Levoleucovorin, which is the enantiomerically active form of folinic acid.IC50 value: Target: Levoleucovorin is used to treat or prevent toxic effects of methotrexate in people who have received methotrexate to treat bone cancer. Levoleucovorin is also used in combination chemotherapy with fluorouracil (5-FU) to treat colorectal cancer that has spread to other parts of the body. This medicine only treats the symptoms of colorectal cancer and does not treat the cancer itself. |
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| Related Catalog | Signaling Pathways >>Cell Cycle/DNA Damage >>AntifolateNatural Products >>AlkaloidResearch Areas >>Cancer |
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| References | [1]. Levomefolic acid. From Wikipedia, the free encyclopedia |
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Chemical & Physical Properties
| Melting Point | 240-250ºC |
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| Molecular Formula | C20H21CaN7O7 |
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| Molecular Weight | 511.501 |
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| Exact Mass | 511.112823 |
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| PSA | 225.50000 |
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| InChIKey | KVUAALJSMIVURS-NQJMHYHOSA-L |
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| SMILES | Nc1nc2c(c(=O)[nH]1)N(C=O)C(CNc1ccc(C(=O)NC(CCC(=O)[O-])C(=O)[O-])cc1)CN2.[Ca+2] |
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| Storage condition | -20°C |
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Synonyms
| folinic acid calcium salt |
| Levoleucovorin calcium (USAN) |
| Calcium (2S)-2-{[4-({[(6S)-2-amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydro-6-pteridinyl]methyl}amino)benzoyl]amino}pentanedioate |
| calcium levofolinate |
| Fusilev (TN) |
| Calcium N-(p-((((6S)-amino-5-formyl-1,4,5,6,7,8-hexahydro-4-oxo-6-pteridinyl)methyl)amino)benzoyl)-L-glutamate (1:1) |
| Isovorin |
| 778XL6VBS8 |
| Calcium 2-{[4-({[(6S)-2-amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)benzoyl]amino}pentanedioate |
| Levofolinate calcium (JAN) |
| Elvorine |
| Levoleucovorin (Calcium) |
| Calcium (2S)-2-{[4-({[(6S)-2-amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)benzoyl]amino}pentanedioate |
| LEVOLEUCOVORIN CALCIUM |
| N-[4-[[[(6S)-2-Amino-5-formyl-1,4,5,6,7,8-hexahydro-4-oxo-6-pteridinyl]methyl]amino]benzoyl]-L-glutamic Acid Calcium Salt (1:1) |
| L-Glutamic acid, N-[4-[[[(6S)-2-amino-5-formyl-1,4,5,6,7,8-hexahydro-4-oxo-6-pteridinyl]methyl]amino]benzoyl]-, calcium salt (1:1) |
| UNII-778XL6VBS8 |
| Isovorin (TN) |
| Calcium levofolinate (INN) |
| MFCD00865527 |
| Levofolinate |
