CAS 108-75-8|2,4,6-Trimethylpyridine

Introduction：Basic information about CAS 108-75-8|2,4,6-Trimethylpyridine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Chemical & Physical Properties
3. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
4. Safety Information
5. Customs
6. Articles25
7. Synonyms

Common Name	2,4,6-Trimethylpyridine
CAS Number	108-75-8	Molecular Weight	121.180
Density	0.9±0.1 g/cm3	Boiling Point	171.0±9.0 °C at 760 mmHg
Molecular Formula	C₈H₁₁N	Melting Point	−43 °C(lit.)
MSDS	ChineseUSA	Flash Point	57.2±0.0 °C
Symbol	GHS02, GHS06	Signal Word	Danger

Names

Name	2,4,6-Collidine
Synonym	More Synonyms

Chemical & Physical Properties

Density	0.9±0.1 g/cm3
Boiling Point	171.0±9.0 °C at 760 mmHg
Melting Point	−43 °C(lit.)
Molecular Formula	C₈H₁₁N
Molecular Weight	121.180
Flash Point	57.2±0.0 °C
Exact Mass	121.089149
PSA	12.89000
LogP	2.11
Vapour Pressure	1.9±0.3 mmHg at 25°C
Index of Refraction	1.502
InChIKey	BWZVCCNYKMEVEX-UHFFFAOYSA-N
SMILES	Cc1cc(C)nc(C)c1
Storage condition	2-8°C
Stability	Stable. Combustible. Incompatible with strong oxidizing agents.
Water Solubility	35 g/L (20 ºC)

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UU0970000

CHEMICAL NAME :: Pyridine, 2,4,6-trimethyl-

CAS REGISTRY NUMBER :: 108-75-8

BEILSTEIN REFERENCE NO. :: 0107283

LAST UPDATED :: 199710

DATA ITEMS CITED :: 7

MOLECULAR FORMULA :: C8-H11-N

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 400 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,847,1986

TYPE OF TEST :: LCLo - Lowest published lethal concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 2500 ppm/2H

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,847,1986

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 1 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,847,1986 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X1347 No. of Facilities: 24 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 712 (estimated) No. of Female Employees: 593 (estimated)

Safety Information

Symbol	GHS02, GHS06
Signal Word	Danger
Hazard Statements	H226-H302 + H332-H311-H315-H319-H335
Precautionary Statements	P261-P280-P305 + P351 + P338-P312
Personal Protective Equipment	Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes	Xn:Harmful;
Risk Phrases	R10;R20/21/22;R36/37/38
Safety Phrases	S26-S36/37
RIDADR	UN 1992 3/PG 3
WGK Germany	3
RTECS	UU0970000
Packaging Group	III
Hazard Class	3
HS Code	2933399010

Customs

HS Code	2933399090
Summary	2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles25

Ambient preparation and reactions of gas phase silver cluster cations and anions.

Phys. Chem. Chem. Phys. 17 , 18364-73, (2015)

Electrospray ionization of metal salt solutions followed by ambient heating transforms the resulting salt clusters into new species, primarily naked ionic metal clusters. The experiment is done by pas...

An easy-to-use excimer fluorescence derivatization reagent, 2-chloro-4-methoxy-6-(4-(pyren-4-yl)butoxy)-1,3,5-triazine, for use in the highly sensitive and selective liquid chromatography analysis of histamine in Japanese soy sauces.

Anal. Chim. Acta 880 , 145-51, (2015)

In this study, a novel pre-column excimer fluorescence derivatization reagent, 2-chloro-4-methoxy-6-(4-(pyren-4-yl)butoxy)-1,3,5-triazine (CMPT), was developed for polyamines, specifically histamine. ...

Biochemical investigations of the mechanism of action of small molecules ZL006 and IC87201 as potential inhibitors of the nNOS-PDZ/PSD-95-PDZ interactions.

Sci. Rep. 5 , 12157, (2015)

ZL006 and IC87201 have been presented as efficient inhibitors of the nNOS/PSD-95 protein-protein interaction and shown great promise in cellular experiments and animal models of ischemic stroke and pa...

Synonyms

Collidine

EINECS 203-613-3

Pyridine, 2,4,6-trimethyl-

γ-collidine

MFCD00006338

2,4,6-trimethylpyridine

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