CAS 23696-28-8|Olaquindox

Introduction：Basic information about CAS 23696-28-8|Olaquindox, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Olaquindox BiologicalActivity
3. Chemical & Physical Properties
4. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
MUTATION DATA
5. Safety Information
6. Customs
7. Articles26
8. Synonyms

Common Name	Olaquindox
CAS Number	23696-28-8	Molecular Weight	263.249
Density	1.4±0.1 g/cm3	Boiling Point	343.3ºC
Molecular Formula	C₁₂H₁₃N₃O₄	Melting Point	209°C (dec.)
MSDS	ChineseUSA	Flash Point	>204.4ºC
Symbol	GHS07, GHS08	Signal Word	Danger

Names

Name	N-(2-hydroxyethyl)-3-methyl-4-oxido-1-oxoquinoxalin-1-ium-2-carboxamide
Synonym	More Synonyms

Olaquindox BiologicalActivity

Description	Olaquindox, a quinoxalin derivative, is an orally active antibiotic veterinary drug. Olaquindox stimulates growth and decreases intestinal mucosal immunity of piglets[1].
Related Catalog	Research Areas >>InfectionSignaling Pathways >>Anti-infection >>Bacterial
In Vivo	Olaquindox (100 mg/kg in the basal diet) improves average daily gain and feed conversion ratio (FCR)[1].
References	[1]. Ding MX, et al. Olaquindox and cyadox stimulate growth and decrease intestinal mucosal immunityof piglets orally inoculated with Escherichia coli. J Anim Physiol Anim Nutr (Berl). 2006 Jun;90(5-6):238-43.

Chemical & Physical Properties

Density	1.4±0.1 g/cm3
Boiling Point	343.3ºC
Melting Point	209°C (dec.)
Molecular Formula	C₁₂H₁₃N₃O₄
Molecular Weight	263.249
Flash Point	>204.4ºC
Exact Mass	263.090607
PSA	100.25000
LogP	-2.20
Index of Refraction	1.651
InChIKey	TURHTASYUMWZCC-UHFFFAOYSA-N
SMILES	Cc1c(C(=O)NCCO)[n+](=O)c2ccccc2n1[O-]
Storage condition	0-6°C

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: VD1582000

CHEMICAL NAME :: 2-Quinoxalinecarboxamide, N-(2-hydroxyethyl)-3-methyl-, 1,4-dioxide

CAS REGISTRY NUMBER :: 23696-28-8

LAST UPDATED :: 199612

DATA ITEMS CITED :: 13

MOLECULAR FORMULA :: C12-H13-N3-O4

MOLECULAR WEIGHT :: 263.28

WISWESSER LINE NOTATION :: T66 BN ENJ BO CVM2Q D1 EO

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1717 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 3316 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 4550 mg/kg/13W-I

TOXIC EFFECTS :: Liver - changes in liver weight Nutritional and Gross Metabolic - weight loss or decreased weight gain Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - other transferases

TYPE OF TEST :: Micronucleus test

TYPE OF TEST :: Micronucleus test

TYPE OF TEST :: Cytogenetic analysis

MUTATION DATA

TYPE OF TEST :: Sister chromatid exchange

TEST SYSTEM :: Rodent - hamster Lung

DOSE/DURATION :: 20 mg/L

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 139,199,1984

Safety Information

Symbol	GHS07, GHS08
Signal Word	Danger
Hazard Statements	H302-H334
Precautionary Statements	P261-P342 + P311
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Faceshields;Gloves
Hazard Codes	Xn:Harmful;
Risk Phrases	R22;R43
Safety Phrases	S36/37
RIDADR	NONH for all modes of transport
RTECS	VD1582000
HS Code	2933990090

Customs

HS Code	2933990090
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles26

First detection of oqxAB in Salmonella spp. isolated from food.

Antimicrob. Agents Chemother. 57(1) , 658-60, (2013)

Food-borne salmonellosis is an important public health problem worldwide and the second leading cause of food-borne illnesses in Hong Kong. In this study, the prevalence and antimicrobial resistance o...

Reduction of carbadox mediated by reaction of Mn(III) with oxalic acid.

Environ. Sci. Technol. 47(3) , 1357-64, (2013)

Manganese(III) geocomponents are commonly found in the soil environment, yet their roles in many biogeochemical processes remain unknown. In this study, we demonstrated that Mn(III) generated from the...

Residue depletion and tissue-plasma correlation of methyl-3-quinoxaline-2-carboxylic acid after dietary administration of olaquindox in pigs.

J. Agric. Food Chem. 58(2) , 937-42, (2010)

A residue depletion study was performed to investigate the tissue kinetics and tissue-plasma correlation of methyl-3-quinoxaline-2-carboxylic acid (MQCA), the marker residue of olaquindox (OLA), in pi...

Synonyms

Bisergon

2-((2-Hydroxyethyl)carbamoyl)-3-methylquinoxaline 1,4-dioxide

MFCD00210341

3-methyl-1,4-dioxy-quinoxaline-2-carboxylic acid 2-hydroxy-ethylamide

EINECS 245-832-7

Olaguindox

Bayernox

Olachindox

Bayonox

Olaquindox

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