CAS 54406-48-3|empenthrin

Introduction：Basic information about CAS 54406-48-3|empenthrin, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Chemical & Physical Properties
3. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
4. Safety Information
5. Customs
6. Articles4
7. Synonyms

Common Name	empenthrin
CAS Number	54406-48-3	Molecular Weight	274.398
Density	1.0±0.1 g/cm3	Boiling Point	346.0±42.0 °C at 760 mmHg
Molecular Formula	C₁₈H₂₆O₂	Melting Point	/
MSDS	ChineseUSA	Flash Point	144.0±25.3 °C
Symbol	GHS07, GHS09	Signal Word	Warning

Names

Name	empenthrin
Synonym	More Synonyms

Chemical & Physical Properties

Density	1.0±0.1 g/cm3
Boiling Point	346.0±42.0 °C at 760 mmHg
Molecular Formula	C₁₈H₂₆O₂
Molecular Weight	274.398
Flash Point	144.0±25.3 °C
Exact Mass	274.193268
PSA	26.30000
LogP	6.35
Vapour Pressure	0.0±0.8 mmHg at 25°C
Index of Refraction	1.527
InChIKey	YUGWDVYLFSETPE-JLHYYAGUSA-N
SMILES	C#CC(OC(=O)C1C(C=C(C)C)C1(C)C)C(C)=CCC
Storage condition	2-8°C
Stability	Stable. Incompatible with strong oxidizing agents.

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: GZ1728000

CHEMICAL NAME :: Cyclopropanecarboxylic acid, 2,2-dimethyl-3-(2-methyl-1-propenyl)-, 1-ethynyl-2-methyl-2- pentenyl ester

CAS REGISTRY NUMBER :: 54406-48-3

LAST UPDATED :: 199806

DATA ITEMS CITED :: 7

MOLECULAR FORMULA :: C18-H26-O2

MOLECULAR WEIGHT :: 274.44

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1680 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: YKYUA6 Yakkyoku. Pharmacy. (Nanzando, 4-1-11, Yushima, Bunkyo-ku, Tokyo, Japan) V.1- 1950- Volume(issue)/page/year: 37,717,1986

TYPE OF TEST :: LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >4610 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JTSCDR Journal of Toxicological Sciences. (Japanese Soc. of Toxicological Sciences, 4th Floor, Gakkai Center Bldg., 4-16, Yayoi 2-chome, Bunkyo-ku, Tokyo 113, Japan) V.1- 1976- Volume(issue)/page/year: 17(Suppl 3),313,1992

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 5 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: YKYUA6 Yakkyoku. Pharmacy. (Nanzando, 4-1-11, Yushima, Bunkyo-ku, Tokyo, Japan) V.1- 1950- Volume(issue)/page/year: 36,533,1985

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >3500 mg/kg

TOXIC EFFECTS :: Peripheral Nerve and Sensation - spastic paralysis with or without sensory change Behavioral - ataxia Kidney, Ureter, Bladder - incontinence

REFERENCE :: JTSCDR Journal of Toxicological Sciences. (Japanese Soc. of Toxicological Sciences, 4th Floor, Gakkai Center Bldg., 4-16, Yayoi 2-chome, Bunkyo-ku, Tokyo 113, Japan) V.1- 1976- Volume(issue)/page/year: 17(Suppl 3),313,1992

TYPE OF TEST :: LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 2300 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JTSCDR Journal of Toxicological Sciences. (Japanese Soc. of Toxicological Sciences, 4th Floor, Gakkai Center Bldg., 4-16, Yayoi 2-chome, Bunkyo-ku, Tokyo 113, Japan) V.1- 1976- Volume(issue)/page/year: 17(Suppl 3),313,1992

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >5 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: YKYUA6 Yakkyoku. Pharmacy. (Nanzando, 4-1-11, Yushima, Bunkyo-ku, Tokyo, Japan) V.1- 1950- Volume(issue)/page/year: 37,717,1986 ** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 18200 mg/kg/26W-I

TOXIC EFFECTS :: Kidney, Ureter, Bladder - other changes Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol) Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - transaminases

REFERENCE :: JTSCDR Journal of Toxicological Sciences. (Japanese Soc. of Toxicological Sciences, 4th Floor, Gakkai Center Bldg., 4-16, Yayoi 2-chome, Bunkyo-ku, Tokyo 113, Japan) V.1- 1976- Volume(issue)/page/year: 17(Suppl 3),313,1992

Safety Information

Symbol	GHS07, GHS09
Signal Word	Warning
Hazard Statements	H302-H411
Precautionary Statements	P273
Personal Protective Equipment	Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes	Xn;N
Risk Phrases	R22;R51/53
Safety Phrases	S61
RIDADR	UN 3082
RTECS	GZ1728000
HS Code	2916209026

Customs

HS Code	2916209026
Summary	2916209026. VAT:17.0%. Tax rebate rate:9.0%. Supervision conditions:S(import or export registration certificate for pesticides). MFN tariff:6.5%. General tariff:30.0%

Articles4

CD11c-positive cells from brain, spleen, lung, and liver exhibit site-specific immune phenotypes and plastically adapt to new environments.

Glia 63(4) , 611-25, (2015)

The brain's immune privilege has been also attributed to the lack of dendritic cells (DC) within its parenchyma and the adjacent meninges, an assumption, which implies maintenance of antigens rather t...

The photochemical behaviour of five household pyrethroid insecticides and a synergist as studied by photo-solid-phase microextraction.

Anal. Bioanal. Chem 388(5-6) , 1235-47, (2007)

In the present study, solid-phase microextraction in photochemical studies was used to investigate UV light induced photodegradation of five pyrethroids (empenthrin, transfluthrin, allethrin, phenothr...

[Mammalian toxicity of empenthrin (Vaporthrin, S-2852F)].

J. Toxicol. Sci. 17 Suppl 3 , 313-34, (1992)

1. Acute toxicity: Empenthrin ((RS)-(EZ)-1-ethynyl-2-methyl-2-pentenyl (1R)-cis/trans-chrysanthemate) caused some toxic signs such as muscular fibrillation, tremor, hypersensitivity, decrease of spont...

Synonyms

(4E)-4-Methylhept-4-en-1-in-3-yl-(1R)-2,2-dimethyl-3-(2-methylprop-1-en-1-yl)cyclopropancarboxylat

(1R)-cis-trans-1-Ethynyl-2-methyl-2-pentenyl 2,2-Dimethyl-3-(2-methyl-1-propenyl)cyclopropanecarboxylate

(4E)-4-Methyl-4-hepten-1-yn-3-yl (1R)-2,2-dimethyl-3-(2-methyl-1-propen-1-yl)cyclopropanecarboxylate

(1RS,2E)-1-ethynyl-2-methylpent-2-enyl (1RS)-cis-trans-2,2-dimethyl-3-(2-methylprop-1-enyl)cyclopropanecarboxylate

EINECS 259-154-4

s2852f

ma108

(1RS,2E)-1-ethynyl-2-methylpent-2-enyl (1RS,3RS

s2852forte

(E)-(RS)-1-Ethynyl-2-methylpent-2-enyl (1R,3RS;1R,3SR)-2,2-Dimethyl-3-(2-methylprop-1-enyl)cyclopropanecarboxylate

Empenthrin

(1R)-2,2-Diméthyl-3-(2-méthyl-1-propèn-1-yl)cyclopropanecarboxylate de (4E)-4-méthyl-4-heptén-1-yn-3-yle

Empenethrin

(4E)-4-Methylhept-4-en-1-yn-3-yl (1R)-2,2-dimethyl-3-(2-methylprop-1-en-1-yl)cyclopropanecarboxylate

Emphenthrin

MFCD01745518

1RS,3SR)-2,2-dimethyl-3-(2-methylprop-1-enyl)cyclopropanecarboxylate

Empenthrin,Pestanal

D-EMPENTHRIN

(2E)-1-ethynyl-2-methyl-2-penten-1-yl 2,2-dimethyl-3-(2-methyl-1-propen-1-yl)cyclopropanecarboxylate

(3Ξ,4E)-4-methylhept-4-en-1-yn-3-yl (1Ξ,3Ξ)-2,2-dimethyl-3-(2-methylprop-1-en-1-yl)cyclopropane-1-carboxylate

(±)-(trans)-1-ethynyl-2-methylpent-2-enyl (±)-cis-trans-chrysanthemate

s2852

Cyclopropanecarboxylic acid, 2,2-dimethyl-3-(2-methyl-1-propen-1-yl)-, (2E)-1-ethynyl-2-methyl-2-penten-1-yl ester, (1R)-

VAPORTHRIN

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