CAS 1405-53-4|Tylosin phosphate

Introduction:Basic information about CAS 1405-53-4|Tylosin phosphate, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameTylosin phosphate
CAS Number1405-53-4Molecular Weight1014.095
Density/Boiling Point980.7ºC at 760 mmHg
Molecular FormulaC46H80NO21PMelting Point/
MSDSChineseUSAFlash Point546.9ºC

Names

NameTylosin phosphate
SynonymMore Synonyms

Tylosin phosphate BiologicalActivity

DescriptionTylosin phosphate(Fradizine; Tylocine; Tylosin A) is a broad spectrum antibiotic against Gram-positive organisms and a limited range of Gram-negative organisms.
Related CatalogSignaling Pathways >>Anti-infection >>BacterialResearch Areas >>Infection
References

[1]. Pilcher CM, et al. Impact of tylosin phosphate and distillers dried grains with solubles on energy and nutrient digestibility and flow through the gastrointestinal tract in growing pigs. J Anim Sci. 2013 Dec;91(12):5687-95.

[2]. Entorf M, et al. Tylosin susceptibility of staphylococci from bovine mastitis. Vet Microbiol. 2014 Jul 16;171(3-4):368-73.

Chemical & Physical Properties

Boiling Point980.7ºC at 760 mmHg
Molecular FormulaC46H80NO21P
Molecular Weight1014.095
Flash Point546.9ºC
Exact Mass1013.496033
PSA326.24000
LogP0.90490
Vapour Pressure0mmHg at 25°C
InChIKeyNBOODGNJLRRJNA-UZEATOBSSA-N
SMILESCCC1OC(=O)CC(O)C(C)C(OC2OC(C)C(OC3CC(C)(O)C(O)C(C)O3)C(N(C)C)C2O)C(CC=O)CC(C)C(=O)C=CC(C)=CC1COC1OC(C)C(O)C(OC)C1OC.O=P(O)(O)O
Storage condition2-8°C

Safety Information

Personal Protective EquipmentEyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard CodesXn
Safety PhrasesS22
RIDADRNONH for all modes of transport
RTECSYP0625000
HS Code2941909000

Customs

HS Code2941909000

Articles4

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Effect of subtherapeutic vs. therapeutic administration of macrolides on antimicrobial resistance in Mannheimia haemolytica and enterococci isolated from beef cattle.

Front. Microbiol. 4 , 133, (2013)

Macrolides are the first-line treatment against bovine respiratory disease (BRD), and are also used to treat infections in humans. The macrolide, tylosin phosphate, is often included in the diet of ca...

[Toxicological studies of a combination of technical tylosin phosphate with bentonite (farmazin TB)].

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Studied were both the acute and subchronic toxicity of technical tylosine phosphate (TP), produced at the Research Chemical and Pharmaceutical Institute, Sofia, used in combination with bentonite, kno...

Synonyms

Pharmasine TB
MFCD06795692
Einecs 215-779-4
Tylan 10 premix
UNII:NR75X12AFF
TYLOSIN PHOSPHATE PREMIX
Farmazin TB
Tylan 40 premix
[(2R,3R,4E,6E,9R,11R,12S,13S,14R)-12-{[3,6-Dideoxy-4-O-(2,6-dideoxy-3-C-methyl-α-L-ribo-hexopyranosyl)-3-(dimethylamino)-β-D-glucopyranosyl]oxy}-2-ethyl-14-hydroxy-5,9,13-trimethyl-8,16-dioxo-1 1-(2-oxoethyl)oxacyclohexadeca-4,6-dien-3-yl]methyl 6-deoxy-2,3-di-O-methyl-β-D-allopyranoside phosphate (1:1)
TylosinPhosphate
TYLAN
Oxacyclohexadeca-11,13-diene-7-acetaldehyde, 15-[[(6-deoxy-2,3-di-O-methyl-β-D-allopyranosyl)oxy]methyl]-6-[[3,6-dideoxy-4-O-(2,6-dideoxy-3-C-methyl-α-L-ribo-hexopyranosyl)-3-(dimethylamino)-be ta-D-glucopyranosyl]oxy]-16-ethyl-4-hydroxy-5,9,13-trimethyl-2,10-dioxo-, (4R,5S,6S,7R,9R,11E,13E,15R,16R)-, phosphate (1:1) (salt)
Tylosin (phosphate)
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