CAS 101831-37-2|Diclazuril
| Common Name | Diclazuril | ||
|---|---|---|---|
| CAS Number | 101831-37-2 | Molecular Weight | 407.638 |
| Density | 1.6±0.1 g/cm3 | Boiling Point | / |
| Molecular Formula | C17H9Cl3N4O2 | Melting Point | 548ºC |
| MSDS | ChineseUSA | Flash Point | / |
Names
| Name | Diclazuril |
|---|---|
| Synonym | More Synonyms |
Diclazuril BiologicalActivity
| Description | Diclazuril is an anti-coccidial drug. Target: AntiparasiticDiclazuril is a coccidiostat, the lambs treated with diclazuril showed an intense, persistent oocyst excretion, with average levels of 97.54 opg, considerably higher than those recorded in the animals treated with toltrazuril (p < 0.05) [1]. Diclazuril is effective against E. maxima later in its life cycle, subclinical intestinal lesions may be present for a short time after infection. Diclazuril was shown in studies to reduce lesion scores and improve performance and health of birds challenged with E. maxima [2]. |
|---|---|
| Related Catalog | Signaling Pathways >>Anti-infection >>ParasiteNatural Products >>OthersResearch Areas >>Infection |
| References | [1]. Diaferia, M., et al., Efficacy of toltrazuril 5 % suspension (Baycox(R), Bayer) and diclazuril (Vecoxan(R), Janssen-Cilag) in the control of Eimeria spp. in lambs. Parasitol Res, 2013. 112 Suppl 1: p. 163-8. [2]. http://www.huvepharma.com/products/view/190 |
Chemical & Physical Properties
| Density | 1.6±0.1 g/cm3 |
|---|---|
| Melting Point | 548ºC |
| Molecular Formula | C17H9Cl3N4O2 |
| Molecular Weight | 407.638 |
| Exact Mass | 405.979095 |
| PSA | 91.54000 |
| LogP | 2.44 |
| Index of Refraction | 1.702 |
| InChIKey | ZSZFUDFOPOMEET-UHFFFAOYSA-N |
| SMILES | N#CC(c1ccc(Cl)cc1)c1c(Cl)cc(-n2ncc(=O)[nH]c2=O)cc1Cl |
| Storage condition | 0-6°C |
Safety Information
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| Hazard Codes | Xn |
| Risk Phrases | R36/37/38:Irritating to eyes, respiratory system and skin . |
| Safety Phrases | S26-S36/37/39 |
| RIDADR | NONH for all modes of transport |
| HS Code | 2933990090 |
Customs
| HS Code | 2933990090 |
|---|---|
| Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
Articles26
More Articles| Increased level of Eimeria sensitivity to diclazuril after using a live coccidial vaccine. Avian Dis. 50(3) , 321-4, (2006) Anticoccidial vaccine and an anticoccidial drug rotation program were compared to determine which program was more effective in producing coccidia populations sensitive of 1 ppm diclazuril. The study ... | |
| Comparison of three adjuvants used to produce polyclonal antibodies to veterinary drugs. Vet. Immunol. Immunopathol. 122(1-2) , 25-34, (2008) Two commercially available adjuvants, Gerbu LQ 3000 and Montanide ISA 50V, were assessed as potential replacements for Freund's adjuvant by evaluating their efficacy in the production of polyclonal an... | |
| Determination of diclazuril, toltrazuril and its two metabolites in poultry tissues and eggs by gel permeation chromatography-liquid chromatography-tandem mass spectrometry. J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 879(20) , 1757-63, (2011) A new procedure has been described for the extraction of diclazuril (DIZ), toltrazuril (TOZ) and its two main metabolites toltrazuril sulphoxide (TZSO) and toltrazuril sulphone (TZS) from poultry tiss... |
Synonyms
| Vecoxan |
| Qiujia |
| MFCD00867203 |
| CLINACOX |
| Nuoqiu |
| DICLAZUTIL |
| clinazox |
