Introduction：Basic information about CAS 74938-88-8|4-Amidinophenylmethanesulfonyl fluoride hydrochloride, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 4-Amidinophenylmethanesulfonyl fluoride hydrochloride |
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| CAS Number | 74938-88-8 | Molecular Weight | 252.69 |
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| Density | / | Boiling Point | 405.2ºC at 760 mmHg |
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| Molecular Formula | C8H10ClFN2O2S | Melting Point | ~205 °C (dec.) |
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| MSDS | USA | Flash Point | 198.8ºC |
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Names
| Name | 4-Amidinophenylmethanesulfonyl fluoride hydrochloride |
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| Synonym | More Synonyms |
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BiologicalActivity
| Description | p-APMSF is an irreversible inhibitor of serinase. p-APMSFhas substrate specificity for positively charged side chains of amino acids,lysine, or arginine. p-APMSF can be used to study the irreversible inhibitionof trypsin and thrombin [1]. |
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| Related Catalog | Research Areas >>OthersSignaling Pathways >>Others >>Others |
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| References | [1]. LauraR, et al. (p-Amidinophenyl)methanesulfonyl fluoride, an irreversible inhibitorof serine proteases. Biochemistry. 1980 Oct 14;19(21):4859-64. |
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Chemical & Physical Properties
| Boiling Point | 405.2ºC at 760 mmHg |
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| Melting Point | ~205 °C (dec.) |
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| Molecular Formula | C8H10ClFN2O2S |
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| Molecular Weight | 252.69 |
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| Flash Point | 198.8ºC |
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| Exact Mass | 252.013550 |
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| PSA | 92.39000 |
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| LogP | 3.45280 |
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| InChIKey | KHLLRHIUKOJXLL-UHFFFAOYSA-N |
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| SMILES | Cl.N=C(N)c1ccc(CS(=O)(=O)F)cc1 |
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| Storage condition | −20°C |
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| Water Solubility | H2O: 50 mM Stable when aliquoted at −20°C. Half-life = 6 minutes in pH 7.0 buffer systems. |
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Safety Information
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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| Hazard Codes | Xn |
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| Risk Phrases | 20/21/22-36/37/38 |
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| Safety Phrases | S22-S24/25 |
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| RIDADR | NONH for all modes of transport |
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| WGK Germany | 3 |
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| HS Code | 2925290090 |
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Customs
| HS Code | 2925290090 |
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| Summary | 2925290090 other imines and their derivatives; salts thereof。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0% |
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Synonyms
| (4-Carbamimidoylphenyl)methanesulfonyl fluoride hydrochloride |
| (4-Carbamimidoylphenyl)methanesulfonyl fluoride hydrochloride (1:1) |
| Benzenemethanesulfonyl fluoride, 4-(aminoiminomethyl)-, hydrochloride (1:1) |
| (4-carbamimidoylphenyl)methanesulfonyl fluoride,hydrochloride |
| MFCD00036898 |
