CAS 5041-81-6|Isoliquiritoside

Introduction：Basic information about CAS 5041-81-6|Isoliquiritoside, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Isoliquiritoside BiologicalActivity
3. Chemical & Physical Properties
4. Synonyms

Common Name	Isoliquiritoside
CAS Number	5041-81-6	Molecular Weight	418.394
Density	1.5±0.1 g/cm3	Boiling Point	743.5±60.0 °C at 760 mmHg
Molecular Formula	C₂₁H₂₂O₉	Melting Point	185-186ºC
MSDS	/	Flash Point	263.3±26.4 °C

Names

Name	isoliquiritin
Synonym	More Synonyms

Isoliquiritoside BiologicalActivity

Description	Isoliquiritin, isolated from Licorice Root, inhibits angiogenesis and tube formation. Isoliquiritin also exhibits antidepressant-like effects and antifungal activity[1][2][3].
Related Catalog	Research Areas >>InfectionSignaling Pathways >>Anti-infection >>FungalResearch Areas >>Inflammation/ImmunologyResearch Areas >>Neurological Disease
References	[1]. Kobayashi S, et al. Inhibitory effect of isoliquiritin, a compound in licorice root, on angiogenesis in vivo and tube formation in vitro. Biol Pharm Bull. 1995 Oct;18(10):1382-6. [2]. Wang W, et al. Antidepressant-like effects of liquiritin and isoliquiritin from Glycyrrhiza uralensis in the forced swimming test and tail suspension test in mice. Prog Neuropsychopharmacol Biol Psychiatry. 2008 Jul 1;32(5):1179-84. [3]. Luo J, et al. Antifungal Activity of Isoliquiritin and Its Inhibitory Effect against Peronophythora litchi Chen through a Membrane Damage Mechanism. Molecules. 2016 Feb 19;21(2):237.

Description

Isoliquiritin, isolated from Licorice Root, inhibits angiogenesis and tube formation. Isoliquiritin also exhibits antidepressant-like effects and antifungal activity[1][2][3].

Related Catalog

Research Areas >>InfectionSignaling Pathways >>Anti-infection >>FungalResearch Areas >>Inflammation/ImmunologyResearch Areas >>Neurological Disease

References

[1]. Kobayashi S, et al. Inhibitory effect of isoliquiritin, a compound in licorice root, on angiogenesis in vivo and tube formation in vitro. Biol Pharm Bull. 1995 Oct;18(10):1382-6.

[2]. Wang W, et al. Antidepressant-like effects of liquiritin and isoliquiritin from Glycyrrhiza uralensis in the forced swimming test and tail suspension test in mice. Prog Neuropsychopharmacol Biol Psychiatry. 2008 Jul 1;32(5):1179-84.

[3]. Luo J, et al. Antifungal Activity of Isoliquiritin and Its Inhibitory Effect against Peronophythora litchi Chen through a Membrane Damage Mechanism. Molecules. 2016 Feb 19;21(2):237.

Chemical & Physical Properties

Density	1.5±0.1 g/cm3
Boiling Point	743.5±60.0 °C at 760 mmHg
Melting Point	185-186ºC
Molecular Formula	C₂₁H₂₂O₉
Molecular Weight	418.394
Flash Point	263.3±26.4 °C
Exact Mass	418.126373
PSA	156.91000
LogP	0.76
Vapour Pressure	0.0±2.6 mmHg at 25°C
Index of Refraction	1.707
InChIKey	YNWXJFQOCHMPCK-LXGDFETPSA-N
SMILES	O=C(C=Cc1ccc(OC2OC(CO)C(O)C(O)C2O)cc1)c1ccc(O)cc1O

Synonyms

2-Propen-1-one, 1-(2,4-dihydroxyphenyl)-3-[4-(β-D-glucopyranosyloxy)phenyl]-, (2E)-

Isoliquiritin

(E)-1-(2,4-dihydroxyphenyl)-3-[4-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]prop-2-en-1-one

2-Propen-1-one, 1-(2,4-dihydroxyphenyl)-3-(4-(β-D-glucopyranosyloxy)phenyl)-, (2E)-

4-[(1E)-3-(2,4-Dihydroxyphenyl)-3-oxo-1-propen-1-yl]phenyl β-D-glucopyranoside

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