CAS 173522-96-8|Lamivudine salicylate

Introduction：Basic information about CAS 173522-96-8|Lamivudine salicylate, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Lamivudine salicylate BiologicalActivity
3. Chemical & Physical Properties
4. Synonyms

Common Name	Lamivudine salicylate
CAS Number	173522-96-8	Molecular Weight	367.377
Density	/	Boiling Point	/
Molecular Formula	C₁₅H₁₇N₃O₆S	Melting Point	/
MSDS	/	Flash Point	/

Names

Name	[(2R,5S)-5-(4-amino-2-oxopyrimidin-1-yl)-1,3-oxathiolan-2-yl]methyl 2-hydroxybenzoate
Synonym	More Synonyms

Lamivudine salicylate BiologicalActivity

Description	Lamivudine (BCH-189) salicylate is an orally active nucleoside reverse transcriptase inhibitor (NRTI). Lamivudine salicylate can inhibit HIV reverse transcriptase 1/2 and also the reverse transcriptase of hepatitis B virus. Lamivudine salicylate can penetrate the CNS[1][2].
Related Catalog	Signaling Pathways >>Anti-infection >>HIVResearch Areas >>InfectionSignaling Pathways >>Anti-infection >>HBVSignaling Pathways >>Anti-infection >>Reverse Transcriptase
References	[1]. Li, Y.C., [A clinical study on lamivudine treatment for advanced schistosomisis with chronic B hepatits]. Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi, 2013. 25(5): p. 548-9, 551. [2]. Zhang, C.E., et al., [Effects of lamivudine on growth of intestinal characteristic bacteria by microcalorimetry in vitro]. Yao Xue Xue Bao, 2013. 48(10): p. 1590-4.

Description

Lamivudine (BCH-189) salicylate is an orally active nucleoside reverse transcriptase inhibitor (NRTI). Lamivudine salicylate can inhibit HIV reverse transcriptase 1/2 and also the reverse transcriptase of hepatitis B virus. Lamivudine salicylate can penetrate the CNS[1][2].

Related Catalog

Signaling Pathways >>Anti-infection >>HIVResearch Areas >>InfectionSignaling Pathways >>Anti-infection >>HBVSignaling Pathways >>Anti-infection >>Reverse Transcriptase

References

[1]. Li, Y.C., [A clinical study on lamivudine treatment for advanced schistosomisis with chronic B hepatits]. Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi, 2013. 25(5): p. 548-9, 551.

[2]. Zhang, C.E., et al., [Effects of lamivudine on growth of intestinal characteristic bacteria by microcalorimetry in vitro]. Yao Xue Xue Bao, 2013. 48(10): p. 1590-4.

Chemical & Physical Properties

Molecular Formula	C₁₅H₁₇N₃O₆S
Molecular Weight	367.377
Exact Mass	367.083801
PSA	173.20000
LogP	1.07750
InChIKey	MUAWHSKZVSAWMH-QWHCGFSZSA-N
SMILES	Nc1ccn(C2CSC(COC(=O)c3ccccc3O)O2)c(=O)n1

Synonyms

2-Hydroxybenzoic acid - 4-amino-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone (1:1)

Benzoic acid, 2-hydroxy-, compd. with 4-amino-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone (1:1)

lamivudine salicylate

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