CAS 469-36-3|24-Methylene cycloartanyl ferulate

Introduction:Basic information about CAS 469-36-3|24-Methylene cycloartanyl ferulate, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common Name24-Methylene cycloartanyl ferulate
CAS Number469-36-3Molecular Weight616.913
Density1.1±0.1 g/cm3Boiling Point668.4±40.0 °C at 760 mmHg
Molecular FormulaC41H60O4Melting Point/
MSDS/Flash Point193.5±20.8 °C

Names

Nameoryzanol
SynonymMore Synonyms

24-Methylene cycloartanyl ferulate BiologicalActivity

Description24-Methylenecycloartanyl ferulate is a γ-oryzanol compound. 24-Methylenecycloartanyl ferulate promotes parvin-beta expression in human breast cancer cells. 24-Methylenecycloartanyl ferulate is a potential ATP-competitive Akt1 inhibitor (EC50= 33.3μM)[1].
Related CatalogResearch Areas >>CancerSignaling Pathways >>PI3K/Akt/mTOR >>Akt
Target

Akt1:33.3 μM (EC50)

References

[1]. Heon Woong Kim, et al. 24-Methylenecycloartanyl ferulate, a major compound of γ-oryzanol, promotes parvin-beta expression through an interaction with peroxisome proliferator-activated receptor-gamma 2 in human breast cancer cells. Biochem Biophys Res Commun. 2015 Dec 25;468(4):574-9.

Chemical & Physical Properties

Density1.1±0.1 g/cm3
Boiling Point668.4±40.0 °C at 760 mmHg
Molecular FormulaC41H60O4
Molecular Weight616.913
Flash Point193.5±20.8 °C
Exact Mass616.449158
PSA55.76000
LogP13.20
Vapour Pressure0.0±2.1 mmHg at 25°C
Index of Refraction1.564

Synonyms

24-Methylenecycloartanyl Ferulate
3-O-feruloylquinic acid
Oryzanol C
3-Feruloylchinasaeure
3-feruloylquinic acid
3-O-ferulyl-24-methylenecycloartanol
5-O-feruloyl quinic acid
24-methylenecycloartanol ferulate
24-methylcycloartanyl ferulate
24-methylene cycloartanyl ferulate
(3β,9β)-24-Methylene-9,19-cyclolanostan-3-yl (2E)-3-(4-hydroxy-3-methoxyphenyl)acrylate
(3β,9β)-24-methylidene-9,19-cyclolanostan-3-yl (2E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoate
24-methylenecycloartanol trans-ferulate
2-propenoic acid, 3-(4-hydroxy-3-methoxyphenyl)-, (3β,9β)-24-methylene-9,19-cyclolanostan-3-yl ester, (2E)-
5-feruloylquinic acid
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