CAS 1078-61-1|3,4-Dihydroxyhydrocinnamic acid

Introduction:Basic information about CAS 1078-61-1|3,4-Dihydroxyhydrocinnamic acid, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common Name3,4-Dihydroxyhydrocinnamic acid
CAS Number1078-61-1Molecular Weight182.173
Density1.4±0.1 g/cm3Boiling Point417.5±30.0 °C at 760 mmHg
Molecular FormulaC9H10O4Melting Point136-139 °C(lit.)
MSDSChineseUSAFlash Point220.4±21.1 °C
Symbol
GHS07
Signal WordWarning

Names

Name3-(3,4-dihydroxyphenyl)propanoic acid
SynonymMore Synonyms

3,4-Dihydroxyhydrocinnamic acid BiologicalActivity

DescriptionDihydrocaffeic acid is a phenolic acid found in Gynura bicolor, reduces phosphorylation of MAPK p38 and prevent UVB-induced skin damage. Antioxidant potential and anti-inflammatory activity[1].
Related CatalogSignaling Pathways >>MAPK/ERK Pathway >>p38 MAPKResearch Areas >>Inflammation/Immunology
Target

p38 MAPK

References

[1]. Oliveira MM, et al. Dihydrocaffeic Acid Prevents UVB-Induced Oxidative Stress Leading to the Inhibition of Apoptosis and MMP-1 Expression via p38 Signaling Pathway. Oxid Med Cell Longev. 2019 Jan 17;2019:2419096.

Chemical & Physical Properties

Density1.4±0.1 g/cm3
Boiling Point417.5±30.0 °C at 760 mmHg
Melting Point136-139 °C(lit.)
Molecular FormulaC9H10O4
Molecular Weight182.173
Flash Point220.4±21.1 °C
Exact Mass182.057907
PSA77.76000
LogP0.50
Vapour Pressure0.0±1.0 mmHg at 25°C
Index of Refraction1.620
InChIKeyDZAUWHJDUNRCTF-UHFFFAOYSA-N
SMILESO=C(O)CCc1ccc(O)c(O)c1

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
MW5143500
CHEMICAL NAME :
Hydrocinnamic acid, 3,4-dihydroxy-
CAS REGISTRY NUMBER :
1078-61-1
BEILSTEIN REFERENCE NO. :
2213449
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C9-H10-O4
MOLECULAR WEIGHT :
182.19

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :
Mutation in mammalian somatic cells
TEST SYSTEM :
Rodent - mouse Lymphocyte
DOSE/DURATION :
150 mg/L
REFERENCE :
EMMUEG Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.10- 1987- Volume(issue)/page/year: 11,523,1988

Safety Information

Symbol
GHS07
Signal WordWarning
Hazard StatementsH315-H319-H335
Precautionary StatementsP261-P305 + P351 + P338
Personal Protective Equipmentdust mask type N95 (US);Eyeshields;Gloves
Hazard CodesXi: Irritant;
Risk PhrasesR36/37/38
Safety PhrasesS26-S36
RIDADRNONH for all modes of transport
WGK Germany3
RTECSMW5143500

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Synonyms

Dihydrocaffeate
3,4-dihydroxy-hydrocinnamicaci
Hydrocaffeate
hydrocaffeic acid
3-propionic acid
3,4-Dihydroxy-benzenepropanoic acid
3,4-Dihydroxydihydrocinnamic acid
3-(3,4-DIHYDROXYPHENYL)PROPIONIC ACID
3,4-Dihydroxybenzenepropionate
3,4-Dihydroxybenzenepropionic acid
dihydrocaffeic acid
3,4-dihydroxyhydrocinnamic acid
3-(3,4-Dihydroxyphenyl)propanoic acid
3-(3,4-Dihydroxyphenyl)propionate
Benzenepropanoic acid, 3,4-dihydroxy-
3,4-DIHYDROCAFFEIC ACID
3,4-Dihydroxyhydrocinnamate
phloretic acid
EINECS 214-083-8
3-(3,4-Dihydroxyphenyl)propionic acid,Hydrocaffeic acid
Dihydrocafeate
MFCD00002776
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