CAS 23477-98-7|Propanamide,N-[(1S,2R,3E,5E,7S,9E,11E,13S,15R,19R)-13-(acetyloxy)-7-hydroxy-1,4,10,19

Introduction：Basic information about CAS 23477-98-7|Propanamide,N-[(1S,2R,3E,5E,7S,9E,11E,13S,15R,19R)-13-(acetyloxy)-7-hydroxy-1,4,10,19, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Chemical & Physical Properties
3. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
4. Synonyms

Common Name	Propanamide,N-[(1S,2R,3E,5E,7S,9E,11E,13S,15R,19R)-13-(acetyloxy)-7-hydroxy-1,4,10,19-tetramethyl-17,18-dioxo-16-oxabicyclo[13.2.2]nonadeca-3,5,9,11-tetraen-2-yl]-2-oxo-,(2S)-
CAS Number	23477-98-7	Molecular Weight	501.56900
Density	1.22g/cm3	Boiling Point	/
Molecular Formula	C₂₇H₃₅NO₈	Melting Point	/
MSDS	/	Flash Point	/

Names

Name	[(4E,6E,10E,12E)-9-hydroxy-6,12,15,18-tetramethyl-16,19-dioxo-14-(2-oxopropanoylamino)-17-oxabicyclo[13.2.2]nonadeca-4,6,10,12-tetraen-3-yl] acetate
Synonym	More Synonyms

Chemical & Physical Properties

Density	1.22g/cm3
Molecular Formula	C₂₇H₃₅NO₈
Molecular Weight	501.56900
Exact Mass	501.23600
PSA	136.07000
LogP	2.67940
Index of Refraction	1.552
InChIKey	LSNBAGMWJRMBEO-JYPWPTKMSA-N
SMILES	CC(=O)OC1C=CC(C)=CCC(O)C=CC(C)=CC(NC(=O)C(C)=O)C2(C)C(=O)OC(C1)C(C)C2=O

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UZ0800000

CHEMICAL NAME :: Pyruvamide, N-(7,13-dihydroxy-1,4,10,19-tetramethyl-17,18-dioxo-1 6-oxabicyclo(13.2.2) nonadeca-3,5,9,11-tetraen-2-yl)-, 13-acetate, (all-E)-(1S,2R,7S,13S,15R,19R)-(-)-

CAS REGISTRY NUMBER :: 23477-98-7

LAST UPDATED :: 199403

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C27-H35-N-O8

MOLECULAR WEIGHT :: 501.63

WISWESSER LINE NOTATION :: T6-17- A B AOV DV IU KU OU QUTJ C1 E1 HOV1 K1 NQ Q1 SMVV1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >10 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year: 14,229,1989

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >10 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year: 14,229,1989

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >10 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: TAKHAA Takeda Kenkyusho Ho. Journal of the Takeda Research Laboratories. (Takeda Yakuhin Kogyo K.K., 2-17-85 Jusohon-machi, Yodogawa-ku, Osaka 532, Japan) V.29- 1970- Volume(issue)/page/year: 41,81,1982

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 6 gm/kg

TOXIC EFFECTS :: Nutritional and Gross Metabolic - weight loss or decreased weight gain Gastrointestinal - other changes Blood - changes in cell count (unspecified)

REFERENCE :: JANTAJ Journal of Antibiotics. (Japan Antibiotics Research Assoc., 2-20-8 Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan) V.2-5, 1948-52; V.21- 1968- Volume(issue)/page/year: 26,647,1973

Synonyms

Ro 23-0731/000

Bundlin B

Lankacidin C-14-acetat,Lankacidin A

Sedecamicina [Spanish]

Lankacidin A

Takelan

Sedecamycinum [Latin]

Sedecamycin

Antibiotic T-2636 A

Lankacidin C 14-acetate

Sedecamycine [French]

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