CHEMICAL IDENTIFICATION - RTECS NUMBER :
- AM1050000
- CHEMICAL NAME :
- Acetonitrile, ((alpha-methylphenethyl)amino)phenyl-
- CAS REGISTRY NUMBER :
- 17590-01-1
- LAST UPDATED :
- 199706
- DATA ITEMS CITED :
- 6
- MOLECULAR FORMULA :
- C17-H18-N2
- MOLECULAR WEIGHT :
- 250.37
- WISWESSER LINE NOTATION :
- NCYR&MY1&1R
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 37600 ug/kg
- TOXIC EFFECTS :
- Cardiac - pulse rate increase, without fall in BP Vascular - BP elevation not characterized in autonomic section Lungs, Thorax, or Respiration - respiratory stimulation
- REFERENCE :
- TOIZAG Toho Igakkai Zasshi. Journal of Medical Society of Toho University. (Toho Daigaku Igakkai, 21-16, Omori-nishi, 5-chome, Ota-ku, Tokyo 143, Japan) V.1- 1954- Volume(issue)/page/year: 24,823,1977
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 58800 ug/kg
- TOXIC EFFECTS :
- Cardiac - pulse rate increase, without fall in BP Vascular - BP elevation not characterized in autonomic section Lungs, Thorax, or Respiration - respiratory stimulation
- REFERENCE :
- TOIZAG Toho Igakkai Zasshi. Journal of Medical Society of Toho University. (Toho Daigaku Igakkai, 21-16, Omori-nishi, 5-chome, Ota-ku, Tokyo 143, Japan) V.1- 1954- Volume(issue)/page/year: 24,823,1977
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 95100 ug/kg
- TOXIC EFFECTS :
- Cardiac - pulse rate increase, without fall in BP Vascular - BP elevation not characterized in autonomic section Lungs, Thorax, or Respiration - respiratory stimulation
- REFERENCE :
- TOIZAG Toho Igakkai Zasshi. Journal of Medical Society of Toho University. (Toho Daigaku Igakkai, 21-16, Omori-nishi, 5-chome, Ota-ku, Tokyo 143, Japan) V.1- 1954- Volume(issue)/page/year: 24,823,1977
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 182 mg/kg
- TOXIC EFFECTS :
- Cardiac - pulse rate increase, without fall in BP Vascular - BP elevation not characterized in autonomic section Lungs, Thorax, or Respiration - respiratory stimulation
- REFERENCE :
- TOIZAG Toho Igakkai Zasshi. Journal of Medical Society of Toho University. (Toho Daigaku Igakkai, 21-16, Omori-nishi, 5-chome, Ota-ku, Tokyo 143, Japan) V.1- 1954- Volume(issue)/page/year: 24,823,1977
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 491 mg/kg
- TOXIC EFFECTS :
- Cardiac - pulse rate increase, without fall in BP Vascular - BP elevation not characterized in autonomic section Lungs, Thorax, or Respiration - respiratory stimulation
- REFERENCE :
- TOIZAG Toho Igakkai Zasshi. Journal of Medical Society of Toho University. (Toho Daigaku Igakkai, 21-16, Omori-nishi, 5-chome, Ota-ku, Tokyo 143, Japan) V.1- 1954- Volume(issue)/page/year: 24,823,1977
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 58 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,335,1972
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