Introduction：Basic information about CAS 67247-11-4|For-Met-Leu-Phe-Lys-OH, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | For-Met-Leu-Phe-Lys-OH |
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| CAS Number | 67247-11-4 | Molecular Weight | 565.73 |
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| Density | / | Boiling Point | / |
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| Molecular Formula | C27H43N5O6S | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | N-Formyl-L-methionyl-L-leucyl-L-phenylalanyl-L-lysine |
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| Synonym | More Synonyms |
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For-Met-Leu-Phe-Lys-OH BiologicalActivity
| Description | N-Formyl-Met-Leu-Phe-Lys (fMLFK) is a peptide, acts as a potent and selective agonist of FPR1, with EC50s of 3.5 nM, 6.7 μM and 0.88 μM for FPR1, FPR2 and FPR2-D2817.32G, respectively[1]. |
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| Related Catalog | Research Areas >>OthersSignaling Pathways >>Others >>Others |
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| Target | EC50: 3.5 nM (FPR1), 6.7 μM (FPR2), 0.88 μM (FPR2-D2817.32G)[1] |
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| References | [1]. He HQ, et al. Structural determinants for the interaction of formyl peptide receptor 2 with peptide ligands. J Biol Chem. 2014 Jan 24;289(4):2295-306. |
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Chemical & Physical Properties
| Molecular Formula | C27H43N5O6S |
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| Molecular Weight | 565.73 |
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| Exact Mass | 565.29300 |
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| PSA | 205.02000 |
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| LogP | 3.71070 |
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| InChIKey | OERILMBTPCSYNG-MLCQCVOFSA-N |
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| SMILES | CSCCC(NC=O)C(=O)NC(CC(C)C)C(=O)NC(Cc1ccccc1)C(=O)NC(CCCCN)C(=O)O |
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Synonyms
| L-Lysine,N-formyl-L-methionyl-L-leucyl-L-phenylalanyl |
| (2S)-6-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-formamido-4-methylsulfanylbutanoyl]amino]-4-methylpentanoyl]amino]-3-phenylpropanoyl]amino]hexanoic acid |
| FOR-MET-LEU-PHE-LYS-OH |
| FOR-MET-LEU-PHE-LYS |
| N-Formyl-Met-Leu-Phe-Lys |
