CAS 88192-20-5|4-Azidobutylamine

Introduction：Basic information about CAS 88192-20-5|4-Azidobutylamine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. 4-Azidobutylamine BiologicalActivity
3. Chemical & Physical Properties
4. Safety Information
5. Customs
6. Synonyms

Common Name	4-Azidobutylamine
CAS Number	88192-20-5	Molecular Weight	114.14900
Density	/	Boiling Point	/
Molecular Formula	C₄H₁₀N₄	Melting Point	/
MSDS	/	Flash Point	/

Names

Name	4-Azidobutan-1-amine
Synonym	More Synonyms

4-Azidobutylamine BiologicalActivity

Description	4-Azidobutylamine is a PROTAC linker, which refers to the alkyl chain composition. 4-Azidobutylamine can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
Related Catalog	Research Areas >>Cancer
References	[1]. Schiedel M, et al. Chemically Induced Degradation of Sirtuin 2 (Sirt2) by a Proteolysis Targeting Chimera (PROTAC) Based on Sirtuin Rearranging Ligands (SirReals). J Med Chem. 2018 Jan 25;61(2):482-491. [2]. Schiedel M, et al. Chemically Induced Degradation of Sirtuin 2 (Sirt2) by a Proteolysis Targeting Chimera (PROTAC) Based on Sirtuin Rearranging Ligands (SirReals). J Med Chem. 2018 Jan 25;61(2):482-491.

Description

4-Azidobutylamine is a PROTAC linker, which refers to the alkyl chain composition. 4-Azidobutylamine can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

Related Catalog

Research Areas >>Cancer

References

[1]. Schiedel M, et al. Chemically Induced Degradation of Sirtuin 2 (Sirt2) by a Proteolysis Targeting Chimera (PROTAC) Based on Sirtuin Rearranging Ligands (SirReals). J Med Chem. 2018 Jan 25;61(2):482-491.

[2]. Schiedel M, et al. Chemically Induced Degradation of Sirtuin 2 (Sirt2) by a Proteolysis Targeting Chimera (PROTAC) Based on Sirtuin Rearranging Ligands (SirReals). J Med Chem. 2018 Jan 25;61(2):482-491.

Chemical & Physical Properties

Molecular Formula	C₄H₁₀N₄
Molecular Weight	114.14900
Exact Mass	114.09100
PSA	75.77000
LogP	1.18866
InChIKey	LFMZGBHJJNIRKH-UHFFFAOYSA-N
SMILES	[N-]=[N+]=NCCCCN

Safety Information

HS Code	2929909090

Customs

HS Code	2929909090
Summary	2929909090 other compounds with other nitrogen function VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Synonyms

6-azidobutylamine

4-Azido-1-butanamine

1-amino-4-azidobutane

4-azido-1-butylamine

1-azido-4-aminobutane

4-azido-butylamine

1-Butanamine,4-azido

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