CAS 28053-08-9|Uridine 5′-diphosphoglucose disodium salt
| Common Name | Uridine 5′-diphosphoglucose disodium salt | ||
|---|---|---|---|
| CAS Number | 28053-08-9 | Molecular Weight | 456.231 |
| Density | 1.9±0.1 g/cm3 | Boiling Point | 780.3±70.0 °C at 760 mmHg |
| Molecular Formula | C15H22N2Na2O17P2 | Melting Point | / |
| MSDS | USA | Flash Point | 425.7±35.7 °C |
Names
| Name | Uridine 5'-Diphosphoglucose Disodium Salt |
|---|---|
| Synonym | More Synonyms |
BiologicalActivity
| Description | Uridine 5′-diphosphoglucose disodium salt (UDP-D-Glucose disodium salt) is the precursor of glucose-containing oligosaccharides, polysaccharides, glycoproteins, and glycolipids in animal tissues and in some microorganisms. Uridine-5′-diphosphoglucose is an agonist of the P2Y14 receptor, a neuroimmune system GPCR[1]. |
|---|---|
| Related Catalog | Signaling Pathways >>Others >>OthersResearch Areas >>Neurological Disease |
| References | [1]. DietrichKeppler, et al. Uridine-5′-diphosphoglucose. Methods of Enzymatic Analysis (Second English Edition). 1974;4:2225-2228. [2]. Das A, et al. Human P2Y(14) receptor agonists: truncation of the hexose moiety of uridine-5'-diphosphoglucose and its replacement with alkyl and aryl groups. J Med Chem. 2010 Jan 14;53(1):471-80. |
Chemical & Physical Properties
| Density | 1.9±0.1 g/cm3 |
|---|---|
| Boiling Point | 780.3±70.0 °C at 760 mmHg |
| Molecular Formula | C15H22N2Na2O17P2 |
| Molecular Weight | 456.231 |
| Flash Point | 425.7±35.7 °C |
| Exact Mass | 456.043396 |
| PSA | 330.11000 |
| LogP | -4.05 |
| Vapour Pressure | 0.0±6.1 mmHg at 25°C |
| Index of Refraction | 1.612 |
| InChIKey | PKJQEQVCYGYYMM-QBNUFUENSA-L |
| SMILES | O=c1ccn(C2OC(COP(=O)([O-])OP(=O)([O-])OC3OC(CO)C(O)C(O)C3O)C(O)C2O)c(=O)[nH]1.[Na+].[Na+] |
| Storage condition | −20°C |
| Water Solubility | H2O: soluble50mg/mL, clear |
Safety Information
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| Risk Phrases | R36/37/38 |
| Safety Phrases | S26-S36 |
| RIDADR | NONH for all modes of transport |
| HS Code | 29400090 |
Articles15
More Articles| Hysteresis in human UDP-glucose dehydrogenase is due to a restrained hexameric structure that favors feedback inhibition. Biochemistry 53(51) , 8043-51, (2014) Human UDP-α-d-glucose-6-dehydrogenase (hUGDH) displays hysteresis because of a slow isomerization from an inactive state (E*) to an active state (E). Here we show that the structure of E* constrains h... | |
| Transporter-mediated uptake of UDP-glucuronic acid by human liver microsomes: assay conditions, kinetics, and inhibition. Drug Metab. Dispos. 43(1) , 147-53, (2014) This study characterized the kinetics, variability, and factors that affect UDP-glucuronic acid (UDP-GlcUA) uptake by human liver microsomes (HLM). Biphasic kinetics were observed for UDP-GlcUA uptake... | |
| UDP-glucose pyrophosphorylase influences polysaccharide synthesis, cell wall components, and hyphal branching in Ganoderma lucidum via regulation of the balance between glucose-1-phosphate and UDP-glucose. Fungal Genet. Biol. 82 , 251-63, (2015) UDP-glucose pyrophosphorylase (UGP) is a key enzyme involved in carbohydrate metabolism, but there are few studies on the functions of this enzyme in fungi. The ugp gene of Ganoderma lucidum was clone... |
Synonyms
| disodium,[[(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-oxidophosphoryl] [(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl] phosphate |
| UDP-Glc UDP-glucose UDPG |
| UDP-glc |
| (3,4-Dihydroxytetrahydro-2-furanyl)methyl 3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl dihydrogen diphosphate |
