Introduction：Basic information about CAS 5614-64-2|8-Hydroxyguanine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 8-Hydroxyguanine |
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| CAS Number | 5614-64-2 | Molecular Weight | 167.12500 |
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| Density | 2.49g/cm3 | Boiling Point | 327.7ºC at 760 mmHg |
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| Molecular Formula | C5H5N5O2 | Melting Point | >400ºC dec. |
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| MSDS | / | Flash Point | 152ºC |
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Names
| Name | 7,8-dihydro-8-oxoguanine |
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| Synonym | More Synonyms |
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8-Hydroxyguanine BiologicalActivity
| Description | 8-Hydroxyguanine is a major pre-mutagenic lesion generated from reactive oxygen species. It causes G-T and A-C substitutions. |
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| Related Catalog | Natural Products >>OthersResearch Areas >>Others |
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| Target | Human Endogenous Metabolite |
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| References | [1]. Arai T, et al. High accumulation of oxidative DNA damage, 8-hydroxyguanine, in Mmh/Ogg1 deficient mice by chronic oxidative stress. Carcinogenesis. 2002 Dec;23(12):2005-10. [2]. Floyd RA, et al. The role of 8-hydroxyguanine in carcinogenesis. Carcinogenesis. 1990 Sep;11(9):1447-50. [3]. Cheng KC, et al. 8-Hydroxyguanine, an abundant form of oxidative DNA damage, causes G----T and A----C substitutions. J Biol Chem. 1992 Jan 5;267(1):166-72. |
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Chemical & Physical Properties
| Density | 2.49g/cm3 |
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| Boiling Point | 327.7ºC at 760 mmHg |
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| Melting Point | >400ºC dec. |
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| Molecular Formula | C5H5N5O2 |
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| Molecular Weight | 167.12500 |
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| Flash Point | 152ºC |
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| Exact Mass | 167.04400 |
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| PSA | 120.94000 |
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| Index of Refraction | 2.156 |
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Safety Information
| Hazard Codes | Xi |
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| Safety Phrases | S24/25 |
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| HS Code | 2933990090 |
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Customs
| HS Code | 2933990090 |
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| Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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Synonyms
| 8-OH-GUA |
| 7,8-DIHYDRO-8-OXOGUANINE |
| 2-AMINO-6,8-DIHYDROXYPURINE |
| 8-Hydroxy-guanin |
| 8-Oxo-7,8-dihydroguanine |
| 8-OXOGUANINE |
| 2-amino-7,9-dihydro-1H-purine-6,8-dione |
| 2-AMINO-6,8-PURINEDIOL |
| 8-Oxodihydroguanine |
| 2-aminopurine-6,8-diol |
| 8-OXOG |
| 8-HYDROXYGUANINE |
| EINECS 227-035-6 |
