CAS 104557-24-6|Desacetylcephapirin sodium

Introduction：Basic information about CAS 104557-24-6|Desacetylcephapirin sodium, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Desacetylcephapirin sodium BiologicalActivity
3. Chemical & Physical Properties
4. Synonyms

Common Name	Desacetylcephapirin sodium
CAS Number	104557-24-6	Molecular Weight	403.40900
Density	/	Boiling Point	/
Molecular Formula	C₁₅H₁₄N₃NaO₅S₂	Melting Point	/
MSDS	/	Flash Point	/

Names

Name	Desacetyl Cephapirin Sodium Salt
Synonym	More Synonyms

Desacetylcephapirin sodium BiologicalActivity

Description	Desacetylcephapirin sodium (Deacetylcephapirin sodium) is an active metabolite of Cephapirin (HY-A0153A). Desacetylcephapirin sodium has antimicrobial against S. aureus and coagulase-negative staphylococci mastitis pathogen[1][2].
Related Catalog	Research Areas >>InfectionSignaling Pathways >>Anti-infection >>Bacterial
Target	antibacterial[2]
In Vitro	Desacetylcephapirin sodium exhibits inhibitory activity on Streptococcus dysgalactiae, with MIC50s both of 0.25 µg/mL for clinical and subclinical bacterial strain[2]. Desacetylcephapirin sodium exhibits inhibitory activity on coagulase-negative staphylococci mastitis pathogen, with MIC50s both of 0.12 µg/mL for clinical and subclinical bacterial strain[2].
References	[1]. B. E. Cabana, et al. Comparative Pharmacokinetics and Metabolism of Cephapirin in Laboratory Animals and Humans. Antimicrob Agents Chemother. 1976 Aug; 10(2): 307–317. [2]. Cristina S Cortinhas, et al. Minimum inhibitory concentrations of cephalosporin compounds and their active metabolites for selected mastitis pathogens. Am J Vet Res. 2013 May;74(5):683-90.

Chemical & Physical Properties

Molecular Formula	C₁₅H₁₄N₃NaO₅S₂
Molecular Weight	403.40900
Exact Mass	403.02700
PSA	176.75000
LogP	0.55530
InChIKey	XYXWZYPKYXORJY-GBWFEORMSA-M
SMILES	O=C(CSc1ccncc1)NC1C(=O)N2C(C(=O)[O-])=C(CO)CSC12.[Na+]

Synonyms

sodium,(6R,7R)-3-(hydroxymethyl)-8-oxo-7-[(2-pyridin-4-ylsulfanylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate

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