CAS 22128-62-7|Chloromethyl chloroformate
Introduction：Basic information about CAS 22128-62-7|Chloromethyl chloroformate, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Chloromethyl chloroformate | ||
|---|---|---|---|
| CAS Number | 22128-62-7 | Molecular Weight | 128.942 |
| Density | 1.5±0.1 g/cm3 | Boiling Point | 107.9±13.0 °C at 760 mmHg |
| Molecular Formula | C2H2Cl2O2 | Melting Point | <-20ºC |
| MSDS | ChineseUSA | Flash Point | 25.5±15.2 °C |
| Symbol | GHS05, GHS06 | Signal Word | Danger |
Names
| Name | chloromethyl carbonochloridate |
|---|---|
| Synonym | More Synonyms |
Chemical & Physical Properties
| Density | 1.5±0.1 g/cm3 |
|---|---|
| Boiling Point | 107.9±13.0 °C at 760 mmHg |
| Melting Point | <-20ºC |
| Molecular Formula | C2H2Cl2O2 |
| Molecular Weight | 128.942 |
| Flash Point | 25.5±15.2 °C |
| Exact Mass | 127.943184 |
| PSA | 26.30000 |
| LogP | 1.14 |
| Vapour Pressure | 26.5±0.2 mmHg at 25°C |
| Index of Refraction | 1.432 |
| InChIKey | JYWJULGYGOLCGW-UHFFFAOYSA-N |
| SMILES | O=C(Cl)OCCl |
Safety Information
| Symbol | GHS05, GHS06 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H314-H331 |
| Precautionary Statements | P261-P280-P305 + P351 + P338-P310 |
| Personal Protective Equipment | Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter |
| Hazard Codes | T:Toxic; |
| Risk Phrases | R23;R34 |
| Safety Phrases | S26-S36/37/39-S45 |
| RIDADR | UN 2745 6.1/PG 2 |
| WGK Germany | 3 |
| Packaging Group | II |
| Hazard Class | 6.1 |
Preparation
Articles3
More Articles| Triazene drug metabolites. Part 17: Synthesis and plasma hydrolysis of acyloxymethyl carbamate derivatives of antitumour triazenes. Bioorg. Med. Chem. 8(7) , 1719-25, (2000) A series of 3-acyloxymethyloxycarbonyl-1-aryl-3-methyltriazenes 5 was synthesised by the sequential reaction of 1-aryl-3-methyltriazenes with (i) chloromethyl chloroformate, (ii) NaI in dry acetone, a... | |
| Aminocarbonyloxymethyl ester prodrugs of flufenamic acid and diclofenac: suppressing the rearrangement pathway in aqueous media. Arch. Pharm. (Weinheim) 340(1) , 32-40, (2007) Aminocarbonyloxymethyl ester prodrugs are known to undergo rearrangement in aqueous solutions to form the corresponding N-acylamine side product via an O-->N intramolecular acyl transfer from the carb... | |
| Water soluble cyclosporine monomethoxy poly(ethyleneglycol) conjugates as potential prodrugs. Arch. Pharm. Res. 27(6) , 662-9, (2004) The highly water-soluble monomethoxypoly(ethyleneglycol) (mPEG) prodrugs of cyclosporin A (CsA) were synthesized. These prodrugs were prepared by initially preparing intermediate in the form of carbon... |
Synonyms
| chloromethoxycarbonyl chloride |
| EINECS 244-793-3 |
| chloromethyl chlorocarbonate |
| chloroformic acid chloromethyl ester |
| Carbonochloridic acid, chloromethyl ester |
| Chloromethyl chloroformate |
| MFCD00077688 |
| Chlorocarbonate de chlorométhyle |
| 1-chloromethyl chloroformate |
| chlormethylchlorocarbonat |
| Chloromethyl carbonochloridate |
