CAS 42542-07-4|1,3-Benzodioxolylbutanamine

Introduction：Basic information about CAS 42542-07-4|1,3-Benzodioxolylbutanamine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Chemical & Physical Properties
3. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
4. Safety Information
5. Articles37
6. Synonyms

Common Name	1,3-Benzodioxolylbutanamine
CAS Number	42542-07-4	Molecular Weight	193.242
Density	1.1±0.1 g/cm3	Boiling Point	297.3±9.0 °C at 760 mmHg
Molecular Formula	C₁₁H₁₅NO₂	Melting Point	/
MSDS	USA	Flash Point	145.5±26.0 °C
Symbol	GHS07	Signal Word	Warning

Names

Name	rac Benzodioxole-5-butanamine Ηydrochloride
Synonym	More Synonyms

Chemical & Physical Properties

Density	1.1±0.1 g/cm3
Boiling Point	297.3±9.0 °C at 760 mmHg
Molecular Formula	C₁₁H₁₅NO₂
Molecular Weight	193.242
Flash Point	145.5±26.0 °C
Exact Mass	193.110275
PSA	44.48000
LogP	2.20
Appearance of Characters	white
Vapour Pressure	0.0±0.6 mmHg at 25°C
Index of Refraction	1.555
InChIKey	LFRHMTZYADABJZ-UHFFFAOYSA-N
SMILES	CCC(N)Cc1ccc2c(c1)OCO2.Cl
Storage condition	?20°C
Water Solubility	H2O: soluble

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: SH6815000

CHEMICAL NAME :: Phenethylamine, alpha-ethyl-3,4-methylenedioxy-, hydrochloride

CAS REGISTRY NUMBER :: 42542-07-4

LAST UPDATED :: 197901

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C11-H15-N-O2.Cl-H

MOLECULAR WEIGHT :: 229.73

WISWESSER LINE NOTATION :: T56 BO DO CHJ G1YZ2 &GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 95 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 25,299,1973

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 82 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 25,299,1973

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: 16 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold Behavioral - rigidity (including catalepsy) Gastrointestinal - nausea or vomiting

REFERENCE :: TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 25,299,1973

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Primate - monkey

DOSE/DURATION :: 20 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold Behavioral - ataxia Lungs, Thorax, or Respiration - dyspnea

REFERENCE :: TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 25,299,1973

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 88 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 25,299,1973

Safety Information

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H302-H312-H332
Precautionary Statements	P280
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xn,T,F
Risk Phrases	20/21/22-39/23/24/25-23/24/25-11
Safety Phrases	36-45-36/37-16-7
RIDADR	UN 2811 6.1 / PGII

Articles37

Small RNAs derived from tRNAs and rRNAs are highly enriched in exosomes from both old and new world Leishmania providing evidence for conserved exosomal RNA Packaging.

BMC Genomics 16 , 151, (2015)

Leishmania use exosomes to communicate with their mammalian hosts and these secreted vesicles appear to contribute to pathogenesis by delivering protein virulence factors to macrophages. In other euka...

Slow and steady cell shrinkage reduces osmotic stress in bovine and murine oocyte and zygote vitrification.

Hum. Reprod. 30(1) , 37-45, (2014)

Does the use of a new cryoprotectant agent (CPA) exchange protocol designed to minimize osmotic stress improve oocyte or zygote vitrification by reducing sublethal cryodamage?The use of a new CPA exch...

Wear particles derived from metal hip implants induce the generation of multinucleated giant cells in a 3-dimensional peripheral tissue-equivalent model.

PLoS ONE 10(4) , e0124389, (2015)

Multinucleate giant cells (MGCs) are formed by the fusion of 5 to 15 monocytes or macrophages. MGCs can be generated by hip implants at the site where the metal surface of the device is in close conta...

Synonyms

Benzodioxolylbutanamine

UNII:CM58WOT28Y

1,3-Benzodioxolylbutanamine

(3,4-Methylenedioxyphenyl)-2-butanamine

3,4-methylenedioxy-α-ethylphenethylamine

1-(1,3-benzodioxol-5-yl)butan-2-amine

α-Ethyl-1,3-benzodioxole-5-ethanamine

1-(1,3-benzodioxol-5-yl)butan-2-amine,hydrochloride

1-(1,3-Benzodioxol-5-yl)-2-butanamine

1,3-Benzodioxole-5-ethanamine, α-ethyl-

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