CAS 83219-99-2|10-HYDROXYWARFARIN

Introduction：Basic information about CAS 83219-99-2|10-HYDROXYWARFARIN, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Chemical & Physical Properties
3. Safety Information
4. Articles12
5. Synonyms

Common Name	10-HYDROXYWARFARIN
CAS Number	83219-99-2	Molecular Weight	324.32700
Density	1.388 g/cm3	Boiling Point	509.2ºC at 760 mmHg
Molecular Formula	C₁₉H₁₆O₅	Melting Point	183-185ºC
MSDS	ChineseUSA	Flash Point	185ºC
Symbol	GHS05, GHS06	Signal Word	Danger

Names

Name	4-hydroxy-3-(2-hydroxy-3-oxo-1-phenylbutyl)chromen-2-one
Synonym	More Synonyms

Chemical & Physical Properties

Density	1.388 g/cm3
Boiling Point	509.2ºC at 760 mmHg
Melting Point	183-185ºC
Molecular Formula	C₁₉H₁₆O₅
Molecular Weight	324.32700
Flash Point	185ºC
Exact Mass	324.10000
PSA	87.74000
LogP	2.58040
Index of Refraction	1.656
InChIKey	BPZSPAZBZFZZBN-UHFFFAOYSA-N
SMILES	CC(=O)C(O)C(c1ccccc1)c1c(O)c2ccccc2oc1=O

Safety Information

Symbol	GHS05, GHS06
Signal Word	Danger
Hazard Statements	H300-H318
Precautionary Statements	P264-P280-P301 + P310-P305 + P351 + P338
Personal Protective Equipment	Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges
Hazard Codes	T: Toxic;
Risk Phrases	25-41
Safety Phrases	26-39-45
RIDADR	UN 2811 6

Articles12

Investigation of two-dimensional high performance liquid chromatography approaches for reversed phase resolution of warfarin and hydroxywarfarin isomers.

J. Chromatogr. A. 1363 , 200-6, (2014)

Several offline and online 2D HPLC methods were investigated for the reversed phase resolution of a complex mixture of closely related warfarin and hydroxywarfarin isomers. By combining reversed phase...

Hydroxywarfarin metabolites potently inhibit CYP2C9 metabolism of S-warfarin.

Chem. Res. Toxicol. 23(5) , 939-45, (2010)

Coumadin (R/S-warfarin) anticoagulant therapy poses a risk to over 50 million Americans, in part due to interpersonal variation in drug metabolism. Consequently, it is important to understand how meta...

Contribution of three CYP3A isoforms to metabolism of R- and S-warfarin.

Drug Metab. Lett. 4(4) , 213-9, (2010)

Effective coumadin (R/S-warfarin) therapy is complicated by inter-individual variability in metabolism. Recent studies have demonstrated that CYP3A isoforms likely contribute to patient responses and ...

Synonyms

10-Hydroxywarfarin

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