Introduction:Basic information about CAS 60008-02-8|Glabrone, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Glabrone |
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| CAS Number | 60008-02-8 | Molecular Weight | 336.33800 |
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| Density | 1.368g/cm3 | Boiling Point | 554.1ºC at 760 mmHg |
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| Molecular Formula | C20H16O5 | Melting Point | / |
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| MSDS | / | Flash Point | 202.6ºC |
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Names
| Name | 7-hydroxy-3-(5-hydroxy-2,2-dimethylchromen-6-yl)chromen-4-one |
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| Synonym | More Synonyms |
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Glabrone BiologicalActivity
| Description | Glabrone is an isoflavone isolated from Glycyrrhiza glabra roots. Glabrone exhibits anti-influenza activity and significant PPAR-γ ligand-binding activity[1][2]. |
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| Related Catalog | Signaling Pathways >>Cell Cycle/DNA Damage >>PPARResearch Areas >>Metabolic Disease |
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| Target | PPAR-γ |
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| References | [1]. Grienke U, et al. Computer-guided approach to access the anti-influenza activity of licorice constituents. J Nat Prod. 2014 Mar 28;77(3):563-70. [2]. Kuroda M, et al. Phenolics from Glycyrrhiza glabra roots and their PPAR-gamma ligand-binding activity. Bioorg Med Chem. 2010 Jan 15;18(2):962-70. |
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Chemical & Physical Properties
| Density | 1.368g/cm3 |
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| Boiling Point | 554.1ºC at 760 mmHg |
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| Molecular Formula | C20H16O5 |
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| Molecular Weight | 336.33800 |
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| Flash Point | 202.6ºC |
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| Exact Mass | 336.10000 |
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| PSA | 79.90000 |
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| LogP | 4.05540 |
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| Index of Refraction | 1.659 |
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| InChIKey | COLMVFWKLOZOOP-UHFFFAOYSA-N |
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| SMILES | CC1(C)C=Cc2c(ccc(-c3coc4cc(O)ccc4c3=O)c2O)O1 |
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Safety Information
| Hazard Codes | Xi |
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| HS Code | 2914400090 |
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Customs
| HS Code | 2914400090 |
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| Summary | 2914400090 other ketone-alcohols and ketone-aldehydes。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0% |
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Synonyms
| 7,5'-dihydroxy-2',2'-dimethyl-2'H-[3,6']bichromenyl-4-one |
| Morusin hydroperoxide |
| 4H-1-Benzopyran-4-one,7-hydroxy-3-(5-hydroxy-2,2-dimethyl-2H-1-benzopyran-6-yl) |
| Glabrone |
| HMS2268B14 |