CAS 60008-02-8|Glabrone

Introduction:Basic information about CAS 60008-02-8|Glabrone, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameGlabrone
CAS Number60008-02-8Molecular Weight336.33800
Density1.368g/cm3Boiling Point554.1ºC at 760 mmHg
Molecular FormulaC20H16O5Melting Point/
MSDS/Flash Point202.6ºC

Names

Name7-hydroxy-3-(5-hydroxy-2,2-dimethylchromen-6-yl)chromen-4-one
SynonymMore Synonyms

Glabrone BiologicalActivity

DescriptionGlabrone is an isoflavone isolated from Glycyrrhiza glabra roots. Glabrone exhibits anti-influenza activity and significant PPAR-γ ligand-binding activity[1][2].
Related CatalogSignaling Pathways >>Cell Cycle/DNA Damage >>PPARResearch Areas >>Metabolic Disease
Target

PPAR-γ

References

[1]. Grienke U, et al. Computer-guided approach to access the anti-influenza activity of licorice constituents. J Nat Prod. 2014 Mar 28;77(3):563-70.

[2]. Kuroda M, et al. Phenolics from Glycyrrhiza glabra roots and their PPAR-gamma ligand-binding activity. Bioorg Med Chem. 2010 Jan 15;18(2):962-70.

Chemical & Physical Properties

Density1.368g/cm3
Boiling Point554.1ºC at 760 mmHg
Molecular FormulaC20H16O5
Molecular Weight336.33800
Flash Point202.6ºC
Exact Mass336.10000
PSA79.90000
LogP4.05540
Index of Refraction1.659
InChIKeyCOLMVFWKLOZOOP-UHFFFAOYSA-N
SMILESCC1(C)C=Cc2c(ccc(-c3coc4cc(O)ccc4c3=O)c2O)O1

Safety Information

Hazard CodesXi
HS Code2914400090

Customs

HS Code2914400090
Summary2914400090 other ketone-alcohols and ketone-aldehydes。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%

Synonyms

7,5'-dihydroxy-2',2'-dimethyl-2'H-[3,6']bichromenyl-4-one
Morusin hydroperoxide
4H-1-Benzopyran-4-one,7-hydroxy-3-(5-hydroxy-2,2-dimethyl-2H-1-benzopyran-6-yl)
Glabrone
HMS2268B14
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