CAS 2465-11-4|Stellasterol

Introduction：Basic information about CAS 2465-11-4|Stellasterol, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Stellasterol BiologicalActivity
3. Chemical & Physical Properties
4. Synonyms

Common Name	Stellasterol
CAS Number	2465-11-4	Molecular Weight	398.66
Density	1.0±0.1 g/cm3	Boiling Point	487.5±44.0 °C at 760 mmHg
Molecular Formula	C₂₈H₄₆O	Melting Point	149-150 °C
MSDS	/	Flash Point	213.0±20.7 °C

Names

Name	5α-ergosta-7,22-dien-3β-ol
Synonym	More Synonyms

Stellasterol BiologicalActivity

Description	Stellasterol is a natural product. Stellasterol has high affinity towards Bcl-2 protein (Ki: 118.05 nM). Stellasterol is a weak α-glucosidase inhibitor[1][2].
Related Catalog	Signaling Pathways >>Apoptosis >>Bcl-2 FamilyResearch Areas >>Others
References	[1]. Lau MF, et al. In vitro and in silico anticancer evaluation of a medicinal mushroom, Ganoderma neo-japonicum Imazeki, against human colonic carcinoma cells. Biotechnol Appl Biochem. 2021 Aug;68(4):902-917. [2]. Krisyanti Budipramana, et al. An Integrated In Silico and In Vitro Assays of Dipeptidyl Peptidase-4 and α-Glucosidase Inhibition by Stellasterol from Ganoderma austral. Sci. Pharm. 2019, 87(3). 21.

Description

Stellasterol is a natural product. Stellasterol has high affinity towards Bcl-2 protein (Ki: 118.05 nM). Stellasterol is a weak α-glucosidase inhibitor[1][2].

Related Catalog

Signaling Pathways >>Apoptosis >>Bcl-2 FamilyResearch Areas >>Others

References

[1]. Lau MF, et al. In vitro and in silico anticancer evaluation of a medicinal mushroom, Ganoderma neo-japonicum Imazeki, against human colonic carcinoma cells. Biotechnol Appl Biochem. 2021 Aug;68(4):902-917.

[2]. Krisyanti Budipramana, et al. An Integrated In Silico and In Vitro Assays of Dipeptidyl Peptidase-4 and α-Glucosidase Inhibition by Stellasterol from Ganoderma austral. Sci. Pharm. 2019, 87(3). 21.

Chemical & Physical Properties

Density	1.0±0.1 g/cm3
Boiling Point	487.5±44.0 °C at 760 mmHg
Melting Point	149-150 °C
Molecular Formula	C₂₈H₄₆O
Molecular Weight	398.66
Flash Point	213.0±20.7 °C
Exact Mass	398.354858
PSA	20.23000
LogP	9.60
Vapour Pressure	0.0±2.8 mmHg at 25°C
Index of Refraction	1.532
InChIKey	QOXPZVASXWSKKU-UEIWAABPSA-N
SMILES	CC(C)C(C)C=CC(C)C1CCC2C3=CCC4CC(O)CCC4(C)C3CCC21C
Storage condition	2-8°C

Synonyms

5alpha-ergosta-7,22-dien-3beta-ol

Ergosta-7,22-dien-3-ol, (3β,5α,22E)-

(3β,5α,22E)-Ergosta-7,22-dien-3-ol

5α-Ergosta-7,22-dien-3β-ol

Stellasterol

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