Introduction：Basic information about CAS 5634-34-4|Ambuphylline, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Ambuphylline |
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| CAS Number | 5634-34-4 | Molecular Weight | 269.30000 |
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| Density | / | Boiling Point | 454.1ºC at 760 mmHg |
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| Molecular Formula | C11H19N5O3 | Melting Point | / |
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| MSDS | / | Flash Point | 228.4ºC |
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Names
| Name | 2-amino-2-methylpropan-1-ol,1,3-dimethyl-7H-purine-2,6-dione |
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| Synonym | More Synonyms |
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Ambuphylline BiologicalActivity
| Description | Ambuphylline (Bufylline) is a bronchodilator. Ambuphylline is a theophylline derivative possibly acting through phosphodiesterase inhibition. Ambuphylline can be used for the research of asthma and other lung diseases[1]. |
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| Related Catalog | Research Areas >>Cardiovascular DiseaseSignaling Pathways >>Metabolic Enzyme/Protease >>Phosphodiesterase (PDE) |
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Chemical & Physical Properties
| Boiling Point | 454.1ºC at 760 mmHg |
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| Molecular Formula | C11H19N5O3 |
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| Molecular Weight | 269.30000 |
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| Flash Point | 228.4ºC |
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| Exact Mass | 269.14900 |
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| PSA | 118.93000 |
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| InChIKey | SEIRRUDMPNNSCY-UHFFFAOYSA-N |
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| SMILES | CC(C)(N)CO.Cn1c(=O)c2[nH]cnc2n(C)c1=O |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- XH4375000
- CAS REGISTRY NUMBER :
- 5634-34-4
- LAST UPDATED :
- 199107
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C7-H8-N4-O2.C4-H11-N-O
- MOLECULAR WEIGHT :
- 269.35
- WISWESSER LINE NOTATION :
- ZX1Q &622 &T56 BM DN FNVMVJ F H &621
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 600 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold
- REFERENCE :
- JLCMAK Journal of Laboratory and Clinical Medicine. (C.V. Mosby Co., 11830 Westline Industrial Dr., St. Louis, MO 63141) V.1- 1915- Volume(issue)/page/year: 31,1337,1946
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 163 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold
- REFERENCE :
- JLCMAK Journal of Laboratory and Clinical Medicine. (C.V. Mosby Co., 11830 Westline Industrial Dr., St. Louis, MO 63141) V.1- 1915- Volume(issue)/page/year: 31,1337,1946
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Synonyms
| Butaphyllamine |
| AMBUPHYLLINE |
| Bufylline |
| EINECS 227-077-5 |
| Theophylline aminoisobutanol |
| Buthoid |
