CAS 108906-69-0|Ilexsaponin B2
Introduction：Basic information about CAS 108906-69-0|Ilexsaponin B2, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Ilexsaponin B2 | ||
|---|---|---|---|
| CAS Number | 108906-69-0 | Molecular Weight | 913.09600 |
| Density | / | Boiling Point | / |
| Molecular Formula | C47H76O17 | Melting Point | / |
| MSDS | / | Flash Point | / |
Names
| Name | ilexsaponin B2 |
|---|
Ilexsaponin B2 BiologicalActivity
| Description | Ilexsaponin B2 is a saponin isolated from the root of Ilex pubescens Hook. et Arn. Ilexsaponin B2 is a potent phosphodiesterase 5 (PDE5) and PDEI inhibitor with IC50 values of 48.8 μM and 477.5 μM, respectively[1]. |
|---|---|
| Related Catalog | Research Areas >>Cardiovascular DiseaseSignaling Pathways >>Metabolic Enzyme/Protease >>Phosphodiesterase (PDE) |
| Target | PDE5:48.8 μM (IC50) PDEI:477.5 μM (IC50) |
| References | [1]. Zichen Liu, et al. Rapid Screening of Potential Phosphodiesterase Inhibitors From the Roots of Ilex pubescens Hook. Et Arn. Using a Combination of Ultrafiltration and LC-MS. Evid Based Complement Alternat Med. 2017;2017:2749643. |
Chemical & Physical Properties
| Molecular Formula | C47H76O17 |
|---|---|
| Molecular Weight | 913.09600 |
| Exact Mass | 912.50800 |
| PSA | 274.75000 |
| LogP | 1.34370 |
| InChIKey | KWHRIYSRPSARCX-FKOHQUDQSA-N |
| SMILES | CC1OC(OC2C(OC3C(OC4CCC5(C)C(CCC6(C)C5CC=C5C7C(C(=O)O)(CCC(C)C7(C)O)CCC56C)C4(C)C)OCC(O)C3O)OC(CO)C(O)C2O)C(O)C(O)C1O |
| Storage condition | 2-8℃ |
