CAS 81446-29-9|(-)-Pinoresinol

Introduction：Basic information about CAS 81446-29-9|(-)-Pinoresinol, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. (-)-Pinoresinol BiologicalActivity
3. Chemical & Physical Properties
4. Safety Information
5. Synonyms

Common Name	(-)-Pinoresinol
CAS Number	81446-29-9	Molecular Weight	358.38500
Density	/	Boiling Point	/
Molecular Formula	C₂₀H₂₂O₆	Melting Point	/
MSDS	/	Flash Point	/

Names

Name	Pinoresinol
Synonym	More Synonyms

(-)-Pinoresinol BiologicalActivity

Description	(-)-Pinoresinol is a plant-derived tetrahydrofuran lignan that inhibits α-glucosidase and acts as a hypoglycemic agent. (-)-Pinoresinol has some anti-inflammatory effects and acts as a chemopreventive agent, inducing increased apoptosis and cell cycle G2/M arrest[1].
Related Catalog	Signaling Pathways >>Apoptosis >>ApoptosisResearch Areas >>Inflammation/Immunology
References	[1]. Lucia Fini, et al. Chemopreventive properties of pinoresinol-rich olive oil involve a selective activation of the ATM-p53 cascade in colon cancer cell lines. Carcinogenesis. 2008 Jan;29(1):139-46. [2]. Alexandrine During, et al. Among plant lignans, pinoresinol has the strongest antiinflammatory properties in human intestinal Caco-2 cells. J Nutr. 2012 Oct;142(10):1798-805.

Description

(-)-Pinoresinol is a plant-derived tetrahydrofuran lignan that inhibits α-glucosidase and acts as a hypoglycemic agent. (-)-Pinoresinol has some anti-inflammatory effects and acts as a chemopreventive agent, inducing increased apoptosis and cell cycle G2/M arrest[1].

Related Catalog

Signaling Pathways >>Apoptosis >>ApoptosisResearch Areas >>Inflammation/Immunology

References

[1]. Lucia Fini, et al. Chemopreventive properties of pinoresinol-rich olive oil involve a selective activation of the ATM-p53 cascade in colon cancer cell lines. Carcinogenesis. 2008 Jan;29(1):139-46.

[2]. Alexandrine During, et al. Among plant lignans, pinoresinol has the strongest antiinflammatory properties in human intestinal Caco-2 cells. J Nutr. 2012 Oct;142(10):1798-805.

Chemical & Physical Properties

Molecular Formula	C₂₀H₂₂O₆
Molecular Weight	358.38500
Exact Mass	358.14200
PSA	77.38000
LogP	3.19020
InChIKey	HGXBRUKMWQGOIE-NSMLZSOPSA-N
SMILES	COc1cc(C2OCC3C(c4ccc(O)c(OC)c4)OCC23)ccc1O

Safety Information

Hazard Codes	Xi

Synonyms

2,6-di(4-hydroxy-3-methoxyphenyl)-3,7-dioxabicyclo[3.3.0]octane

(+)-syringaresinol

pinoresinol monomethyl ether

pinoresinol

(7S,7'S,8R,8'R)-3,3'-dimethoxy-7,9':7',9-diepoxylignane-4,4'-diol

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