CAS 178307-42-1|Revaprazan Hydrochloride

Introduction：Basic information about CAS 178307-42-1|Revaprazan Hydrochloride, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Revaprazan Hydrochloride BiologicalActivity
3. Chemical & Physical Properties
4. Synonyms

Common Name	Revaprazan Hydrochloride
CAS Number	178307-42-1	Molecular Weight	398.904
Density	/	Boiling Point	/
Molecular Formula	C₂₂H₂₄ClFN₄	Melting Point	205-208°
MSDS	/	Flash Point	/

Names

Name	Revaprazan Hydrochloride
Synonym	More Synonyms

Revaprazan Hydrochloride BiologicalActivity

Description	Revaprazan hydrochloride is a novel acid pump antagonist (APA). Revaprazan hydrochloride reduces COX-2 expression and has significant anti-inflammatory actions activities in H. pylori infection[1].
Related Catalog	Research Areas >>InfectionSignaling Pathways >>Immunology/Inflammation >>COXSignaling Pathways >>Anti-infection >>Bacterial
Target	Acid pump; COX-2[1]
References	[1]. Lee JS, et al. Revaprazan, a novel acid pump antagonist, exerts anti-inflammatory action against Helicobacter pylori-induced COX-2 expression by inactivating Akt signaling. J Clin Biochem Nutr. 2012 Sep;51(2):77-83.

Chemical & Physical Properties

Melting Point	205-208°
Molecular Formula	C₂₂H₂₄ClFN₄
Molecular Weight	398.904
Exact Mass	398.167358
PSA	41.05000
LogP	6.03980
InChIKey	MALPZYQJEDBIAK-UHFFFAOYSA-N
SMILES	Cc1nc(Nc2ccc(F)cc2)nc(N2CCc3ccccc3C2C)c1C.Cl
Storage condition	2-8°C

Synonyms

T66 CNT&J B1 C- DT6N CNJ BMR DF& E1 F1 &&HCl

N-(4-Fluorophenyl)-4,5-dimethyl-6-(1-methyl-3,4-dihydro-2(1H)-isoquinolinyl)-2-pyrimidinamine hydrochloride (1:1)

4-(3,4-Dihydro-1-methyl-2(1H)-isoquinolinyl)-N-(4-fluorophenyl)-5,6-dimethyl-2-pyrimidinamine, monohydrochloride

N-(4-Fluorophenyl)-4,5-dimethyl-6-(1-methyl-3,4-dihydroisoquinolin-2(1H)-yl)pyrimidin-2-amine hydrochloride

Revanex

2-Pyrimidinamine, 4-(3,4-dihydro-1-methyl-2(1H)-isoquinolinyl)-N-(4-fluorophenyl)-5,6-dimethyl-, monohydrochloride

Revaprazan HCL

2-Pyrimidinamine, 4-(3,4-dihydro-1-methyl-2(1H)-isoquinolinyl)-N-(4-fluorophenyl)-5,6-dimethyl-, hydrochloride (1:1)

YH1885

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