Introduction：Basic information about CAS 62-13-5|Adrenalone hydrochloride, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Adrenalone hydrochloride |
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| CAS Number | 62-13-5 | Molecular Weight | 217.650 |
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| Density | / | Boiling Point | 405.6ºC at 760 mmHg |
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| Molecular Formula | C9H12ClNO3 | Melting Point | 244-249 °C (dec.) |
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| MSDS | USA | Flash Point | / |
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Names
| Name | 1-(3,4-dihydroxyphenyl)-2-(methylamino)ethanone,hydrochloride |
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| Synonym | More Synonyms |
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Adrenalone hydrochloride BiologicalActivity
| Description | Adrenalone hydrochloride is a selective α1-adrenoceptor agonist, used as a topical vasoconstrictor and hemostatic, used to prolong the action of local anesthetics. |
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| Related Catalog | Signaling Pathways >>GPCR/G Protein >>Adrenergic ReceptorResearch Areas >>Others |
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Chemical & Physical Properties
| Boiling Point | 405.6ºC at 760 mmHg |
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| Melting Point | 244-249 °C (dec.) |
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| Molecular Formula | C9H12ClNO3 |
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| Molecular Weight | 217.650 |
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| Exact Mass | 217.050568 |
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| PSA | 69.56000 |
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| LogP | 1.69280 |
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| InChIKey | CSRRBDMYOUQTCO-UHFFFAOYSA-N |
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| SMILES | CNCC(=O)c1ccc(O)c(O)c1.Cl |
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| Storage condition | 2-8°C |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- AM8225000
- CHEMICAL NAME :
- Acetophenone, 3',4'-dihydroxy-2-(methylamino)-, hydrochloride
- CAS REGISTRY NUMBER :
- 62-13-5
- LAST UPDATED :
- 199009
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C9-H11-N-O3.Cl-H
- MOLECULAR WEIGHT :
- 217.67
- WISWESSER LINE NOTATION :
- QR BQ DV1M1 &GH
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 80 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 71,62,1941
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 902 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 92,369,1948
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Safety Information
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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| Safety Phrases | S22-S24/25 |
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| RIDADR | NONH for all modes of transport |
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| WGK Germany | 3 |
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| RTECS | AM8225000 |
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| HS Code | 2922509090 |
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Customs
| HS Code | 2922509090 |
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| Summary | 2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
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Articles3
More Articles
| [Radiation protective effect of beta-ketoanalogs of hydroxyphenyl ethanolamines]. Radiats. Biol. Radioecol. 37(6) , 914-7, (1997) Experiments are carried out on 3400 mice, irradiated in dose 8 Gy (LD97/30). beta-Ketoanalogs of adrenaline (adrenalone, 50-150 mumol/kg), m,p-dipivaloyladrenaline (20 mumol/kg) and phenylephrine (but... | |
| Electron spin resonance-spin stabilization of semiquinones produced during oxidation of epinephrine and its analogues. J. Biol. Chem. 259(1) , 354-8, (1984) The ESR-spin stabilization approach has been employed to detect and characterize o-semiquinone radicals from the oxidation of epinephrine and related materials (norepinephrine, 3,4-dihydroxynorephedri... | |
| Formation of adrenaline in the iris-ciliary body from adrenalone diesters. Exp. Eye Res. 38(6) , 621-6, (1984) Many diesters of adrenalone have high ocular sympathomimetic activity although adrenalone itself, even if delivered intraocularly, is practically inactive. Thus these diesters cannot be considered pro... | |
Synonyms
| 3',4'-Dihydroxy-2-(methylamino)acetophenone hydrochloride |
| Adrenalonium chloratum |
| 1-(3,4-dihydroxyphenyl)-1-oxo-2-methylamino-ethan-hydrochlorid |
| ADRENALONE,HYDROCHLORIDE |
| Epinephrine ketone hydrochloride |
| MFCD00035075 |
| Adrenalone HCL |
| Stryphnonasal |
| [2-(3,4-dihydroxyphenyl)-2-oxoethyl]methylammonium chloride |
| Acetophenone, 3',4'-dihydroxy-2- (methylamino)-, hydrochloride |
| Ethanone, 1-(3,4-dihydroxyphenyl)-2-(methylamino)-, hydrochloride (9CI) |
| α-Methylamino-3',4'-dihydroxyacetophenone hydrochloride |
| 1-(3,4-Dihydroxy-phenyl)-2-methylamino-aethanon,Hydrochlorid |
| 1-(3,4-dihydroxy-phenyl)-2-methylamino-ethanone,hydrochloride |
| Adrenone hydrochloride |
| adrenalon hydrochloride |
| EINECS 200-525-7 |
| Kephrine hydrochloride |
| Ethanone, 1- (3,4-dihydroxyphenyl)-2-(methylamino)-, hydrochloride |
| 1-(3,4-Dihydroxyphenyl)-2-(methylamino)ethanone hydrochloride (1:1) |
| Adrenalone hydrochloride |
| Ethanone, 1-(3,4-dihydroxyphenyl)-2-(methylamino)-, hydrochloride (1:1) |
| Adrenalone (hydrochloride) |
