Introduction：Basic information about CAS 50-99-7|D-(+)-Glucose, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | D-(+)-Glucose |
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| CAS Number | 50-99-7 | Molecular Weight | 180.156 |
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| Density | 1.6±0.1 g/cm3 | Boiling Point | 527.1±50.0 °C at 760 mmHg |
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| Molecular Formula | C6H12O6 | Melting Point | 146 ºC |
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| MSDS | ChineseUSA | Flash Point | 286.7±26.6 °C |
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Names
| Name | aldehydo-D-glucose |
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| Synonym | More Synonyms |
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D-(+)-Glucose BiologicalActivity
| Description | Dextrose, a simple sugar (monosaccharide), is an important carbohydrate in biology.Target: OthersDextrose(D-glucose), a simple sugar (monosaccharide), is an important carbohydrate in biology. |
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| Related Catalog | Research Areas >>Metabolic DiseaseNatural Products >>Saccharides and Glycosides |
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| Target | Human Endogenous Metabolite |
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Chemical & Physical Properties
| Density | 1.6±0.1 g/cm3 |
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| Boiling Point | 527.1±50.0 °C at 760 mmHg |
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| Melting Point | 146 ºC |
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| Molecular Formula | C6H12O6 |
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| Molecular Weight | 180.156 |
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| Flash Point | 286.7±26.6 °C |
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| Exact Mass | 180.063385 |
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| PSA | 118.22000 |
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| LogP | -3.17 |
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| Vapour Pressure | 0.0±3.1 mmHg at 25°C |
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| Index of Refraction | 1.573 |
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| InChIKey | GZCGUPFRVQAUEE-UHFFFAOYSA-N |
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| SMILES | O=CC(O)C(O)C(O)C(O)CO |
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| Water Solubility | Soluble |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- LZ6600000
- CHEMICAL NAME :
- D-Glucose
- CAS REGISTRY NUMBER :
- 50-99-7
- BEILSTEIN REFERENCE NO. :
- 1724615
- LAST UPDATED :
- 199710
- DATA ITEMS CITED :
- 28
- MOLECULAR FORMULA :
- C6-H12-O6
- MOLECULAR WEIGHT :
- 180.18
- WISWESSER LINE NOTATION :
- T6OTJ BQ CQ DQ EQ F1Q -D,GLU
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 25800 mg/kg
- TOXIC EFFECTS :
- Behavioral - coma Lungs, Thorax, or Respiration - cyanosis Gastrointestinal - hypermotility, diarrhea
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 18 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 9 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- 8 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 20 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 12 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 15400 gm/kg/22W-C
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Tumorigenic - tumors at site of application
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 2 gm/kg
- SEX/DURATION :
- female 28 week(s) after conception
- TOXIC EFFECTS :
- Reproductive - Specific Developmental Abnormalities - craniofacial (including nose and tongue) Reproductive - Specific Developmental Abnormalities - other developmental abnormalities
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intravenous
- DOSE :
- 2 gm/kg
- SEX/DURATION :
- female 39 week(s) after conception
- TOXIC EFFECTS :
- Reproductive - Maternal Effects - other effects Reproductive - Effects on Embryo or Fetus - other effects to embryo
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intravenous
- DOSE :
- 1057 ug/kg
- SEX/DURATION :
- female 39 week(s) after conception
- TOXIC EFFECTS :
- Reproductive - Specific Developmental Abnormalities - hepatobiliary system
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intravenous
- DOSE :
- 1300 mg/kg
- SEX/DURATION :
- female 39 week(s) after conception
- TOXIC EFFECTS :
- Reproductive - Effects on Newborn - biochemical and metabolic Reproductive - Effects on Newborn - behavioral
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- DOSE :
- 300 gm/kg
- SEX/DURATION :
- female 30 day(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Maternal Effects - ovaries, fallopian tubes Reproductive - Maternal Effects - uterus, cervix, vagina
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- DOSE :
- 20 gm/kg
- SEX/DURATION :
- female 6-8 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Specific Developmental Abnormalities - eye/ear
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- DOSE :
- 20 gm/kg
- SEX/DURATION :
- female 6-8 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Specific Developmental Abnormalities - eye/ear
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Multiple routes
- DOSE :
- 20 gm/kg
- SEX/DURATION :
- female 6-8 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Specific Developmental Abnormalities - eye/ear Reproductive - Specific Developmental Abnormalities - musculoskeletal system
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Multiple routes
- DOSE :
- 20 mg/kg
- SEX/DURATION :
- female 6-8 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Specific Developmental Abnormalities - urogenital system
MUTATION DATA - TYPE OF TEST :
- Mutation in mammalian somatic cells
- TEST SYSTEM :
- Rodent - mouse Lymphocyte
- DOSE/DURATION :
- 179 mmol/L
- REFERENCE :
- MUTAEX Mutagenesis. (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1986- Volume(issue)/page/year: 3,193,1988 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 81836 No. of Facilities: 16738 (estimated) No. of Industries: 117 No. of Occupations: 90 No. of Employees: 136870 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 81836 No. of Facilities: 11017 (estimated) No. of Industries: 86 No. of Occupations: 102 No. of Employees: 363666 (estimated) No. of Female Employees: 186490 (estimated)
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Safety Information
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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| Hazard Codes | Xi |
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| Risk Phrases | R36/37/38 |
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| Safety Phrases | S26-S36/37-S24/25 |
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| RIDADR | NONH for all modes of transport |
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| WGK Germany | 1 |
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| RTECS | LZ6600000 |
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| HS Code | 2940000000 |
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Customs
| HS Code | 2912491000 |
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| Summary | 2912491000. other aldehyde-alcohols. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:5.5%. General tariff:30.0% |
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Synonyms
| D-(+)-Glucose,Dextrose |
| D-Glucose |
| D(+)-Glucose |
| EINECS 200-075-1 |
| MFCD00063684 |
| D-(+)-Glucose |
| D-(+)-Dextrose |
| aldehydo-D-glucose |
| (2R,3S,4R,5R)-2,3,4,5,6-Pentahydroxyhexanal |
| Glucose |
| Dextrose |
