CAS 951-77-9|2'-Deoxycytidine monohydrate

Introduction：Basic information about CAS 951-77-9|2'-Deoxycytidine monohydrate, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. 2'-Deoxycytidine monohydrate BiologicalActivity
3. Chemical & Physical Properties
4. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
MUTATION DATA
5. Safety Information
6. Articles168
7. Synonyms

Common Name	2'-Deoxycytidine monohydrate
CAS Number	951-77-9	Molecular Weight	227.22
Density	1.7±0.1 g/cm3	Boiling Point	482.1±55.0 °C at 760 mmHg
Molecular Formula	C₉H₁₃N₃O₄	Melting Point	209-211 °C(lit.)
MSDS	USA	Flash Point	245.4±31.5 °C

Names

Name	2'-deoxycytidine
Synonym	More Synonyms

2'-Deoxycytidine monohydrate BiologicalActivity

Description	2'-Deoxycytidine, a deoxyribonucleoside, could inhibit biological effects of Bromodeoxyuridine (Brdu).
Related Catalog	Natural Products >>Saccharides and GlycosidesResearch Areas >>Others
Target	Human Endogenous Metabolite Brdu
References	[1]. Horn D, et al. Inhibition of biological effects of bromodeoxyuridine by deoxycytidine: correlation with decreased incorporation of bromodeoxyuridine into DNA. Somatic Cell Genet. 1976 Sep;2(5):469-81.

Chemical & Physical Properties

Density	1.7±0.1 g/cm3
Boiling Point	482.1±55.0 °C at 760 mmHg
Melting Point	209-211 °C(lit.)
Molecular Formula	C₉H₁₃N₃O₄
Molecular Weight	227.22
Flash Point	245.4±31.5 °C
PSA	119.83000
LogP	-1.73
Vapour Pressure	0.0±2.7 mmHg at 25°C
Index of Refraction	1.720
InChIKey	CKTSBUTUHBMZGZ-SHYZEUOFSA-N
SMILES	Nc1ccn(C2CC(O)C(CO)O2)c(=O)n1
Storage condition	Store at RT.
Water Solubility	H2O: 50 mg/mL, clear, colorless

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: HA3800000

CHEMICAL NAME :: Cytidine, 2'-deoxy-

CAS REGISTRY NUMBER :: 951-77-9

BEILSTEIN REFERENCE NO. :: 0087567

LAST UPDATED :: 199701

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C9-H13-N3-O4

MOLECULAR WEIGHT :: 227.25

WISWESSER LINE NOTATION :: T6NVNJ DZ A- ET5OTJ B1Q CQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intraperitoneal

DOSE :: 800 mg/kg

SEX/DURATION :: female 9 day(s) after conception

TOXIC EFFECTS :: Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants)

MUTATION DATA

TYPE OF TEST :: DNA inhibition

TEST SYSTEM :: Rodent - hamster Lung

DOSE/DURATION :: 1 mmol/L

REFERENCE :: BICMBE Biochimie. (SPPIF, B.P.22, F-41353 Vineuil, France) V.53- 1971- Volume(issue)/page/year: 64,809,1982

Safety Information

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes	Xi
Safety Phrases	S24/25
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	HA3800000

Articles168

Quantitation of endogenous nucleoside triphosphates and nucleosides in human cells by liquid chromatography tandem mass spectrometry.

Anal. Bioanal. Chem 407(13) , 3693-704, (2015)

Nucleosides and nucleoside triphosphates are the building blocks of nucleic acids and important bioactive metabolites, existing in all living cells. In the present study, two liquid chromatography tan...

Simultaneous quantification of purine and pyrimidine bases, nucleosides and their degradation products in bovine blood plasma by high performance liquid chromatography tandem mass spectrometry.

J. Chromatogr. A. 1356 , 197-210, (2014)

Improved nitrogen utilization in cattle is important in order to secure a sustainable cattle production. As purines and pyrimidines (PP) constitute an appreciable part of rumen nitrogen, an improved u...

Kinetic parameters and recognition of thymidine analogues with varying functional groups by thymidine phosphorylase.

Bioorg. Med. Chem. 16 , 3866-70, (2008)

Thymidine phosphorylase (TP, EC 2.4.2.4) recognized the structure of the substrate with high specificity, via both the base and the ribosyl moieties. The replacement of 3'-OH of thymidine markedly inf...

Synonyms

1-(2-Deoxy-β-D-ribofuranosyl)cytosine

EINECS 213-454-1

4-Amino-1-(2-deoxy-β-D-erythro-pentofuranosyl)-2(1H)-pyrimidinone

4-Amino-1-(2-deoxy-β-D-glycero-pentofuranosyl)pyrimidin-2(1H)-one

2-pyrimidinol, 1-(2-deoxy-β-D-erythro-pentofuranosyl)-1,4-dihydro-4-imino-

Cytidine, 2'-deoxy-

1-(2-Deoxy-β-D-erythro-pentofuranosyl)-4-imino-1,4-dihydro-2-pyrimidinol

1-(2-Deoxy-b-D-ribofuranosyl)cytosine

deoxycytidine

2'-Deoxycytidine monohydrate

4-Amino-1-(2-deoxy-b-D-erythro-pentofuranosyl)-2(1H)-pyrimidinone

2(1H)-pyrimidinone, 4-amino-1-(2-deoxy-β-D-glycero-pentofuranosyl)-

2‘-Deoxycytidine

1-(2-deoxy-β-D-erythro-pentofuranosyl)-Cytosine

MFCD00006547

Recommended......