Introduction：Basic information about CAS 3736-77-4|2,2'-Cyclouridine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 2,2'-Cyclouridine |
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| CAS Number | 3736-77-4 | Molecular Weight | 226.186 |
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| Density | 2.0±0.1 g/cm3 | Boiling Point | 456.3±55.0 °C at 760 mmHg |
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| Molecular Formula | C9H10N2O5 | Melting Point | 239-240ºC |
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| MSDS | USA | Flash Point | 229.8±31.5 °C |
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Names
| Name | 2,2'-O-Anhydro-(1-β-D-arabinofuranosyl)uracil |
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| Synonym | More Synonyms |
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2,2'-Cyclouridine BiologicalActivity
| Description | 2,2'-Anhydrouridine is used for anticancer and antiviral research[1]. |
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| Related Catalog | Signaling Pathways >>Others >>OthersResearch Areas >>CancerResearch Areas >>Infection |
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| References | [1]. Drabikowska AK, et al. Inhibitor properties of some 5-substituted uracil acyclonucleosides, and 2,2'-anhydrouridines versus uridine phosphorylase from E. coli and mammalian sources. Biochem Pharmacol. 1987 Dec 1;36(23):4125-8. |
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Chemical & Physical Properties
| Density | 2.0±0.1 g/cm3 |
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| Boiling Point | 456.3±55.0 °C at 760 mmHg |
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| Melting Point | 239-240ºC |
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| Molecular Formula | C9H10N2O5 |
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| Molecular Weight | 226.186 |
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| Flash Point | 229.8±31.5 °C |
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| Exact Mass | 226.058975 |
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| PSA | 93.81000 |
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| LogP | -1.40 |
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| Vapour Pressure | 0.0±2.5 mmHg at 25°C |
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| Index of Refraction | 1.816 |
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| InChIKey | UUGITDASWNOAGG-CCXZUQQUSA-N |
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| SMILES | O=c1ccn2c(n1)OC1C(O)C(CO)OC12 |
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| Storage condition | Store at RT. |
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Safety Information
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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| Hazard Codes | T+ |
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| Safety Phrases | 24/25 |
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| RIDADR | NONH for all modes of transport |
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| WGK Germany | 3 |
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| HS Code | 29349990 |
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Articles5
More Articles
| 2,2'-Anhydro-1-(3',5'-di-O-acetyl-β-D-arabinofuranosyl)uracil, a cyclouridine nucleoside with a C4'-endo furanosyl conformation. Acta Crystallogr. C 69(Pt 3) , 282-4, (2013) 2,2'-Anhydro-1-(3',5'-di-O-acetyl-β-D-arabinofuranosyl)uracil, C13H14N2O7, was obtained by refluxing 2',3'-O-(methoxymethylene)uridine in acetic anhydride. The structure exhibits a nearly perfect C4'-... | |
Aldrichimica Acta 20 , 52, (1987)
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| Inhibitor properties of some 5-substituted uracil acyclonucleosides, and 2,2'-anhydrouridines versus uridine phosphorylase from E. coli and mammalian sources. Biochem. Pharmacol. 36(23) , 4125-8, (1987) Two series of 5-substituted uracil N(1)-acyclonucleosides, each with a different acyclic chain, were examined as inhibitors of uridine phosphorylase from rat intestinal mucosa, and several against the... | |
Synonyms
| O2,2'-Cyclouridine |
| EINECS 223-107-6 |
| 2,2'-Cyclouridine |
| 2,2'-O-Cyclouridine |
| MFCD00004945 |
| 2,2-Anhydro-1(b-D-arabinofuranosyl)uracil |
| 2,2'-Anhydro-1(B-D-arabinofuranosyl)uracil |
| 2,2′-O-Cyclouridine |
| 6H-Furo[2',3':4,5]oxazolo[3,2-a]pyrimidin-6-one, 2,3,3a,9a-tetrahydro-3-hydroxy-2-(hydroxymethyl)-, (2R,3R,3aS,9aR)- |
| O2,2'-Cyclouridine (VAN) |
| (2R,3R,3aS,9aR)-3-Hydroxy-2-(hydroxymethyl)-2,3,3a,9a-tetrahydro-6H-furo[2',3':4,5][1,3]oxazolo[3,2-a]pyrimidin-6-one |
| 2,2'-Anhydrouridine |
