CAS 37271-17-3|Sennoside D

Introduction:Basic information about CAS 37271-17-3|Sennoside D, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameSennoside D
CAS Number37271-17-3Molecular Weight848.756
Density1.7±0.1 g/cm3Boiling Point1130.3±65.0 °C at 760 mmHg
Molecular FormulaC42H40O19Melting Point/
MSDSChineseUSAFlash Point344.4±27.8 °C

Names

NameSennoside D
SynonymMore Synonyms

Sennoside D BiologicalActivity

DescriptionSennoside D is an anthraquinone glycoside, found in leaves and pods of Senna (Cassia angustifolia)[1].
Related CatalogResearch Areas >>OthersSignaling Pathways >>Others >>Others
References

[1]. Rama Reddy NR, et al. Next Generation Sequencing and Transcriptome Analysis Predicts Biosynthetic Pathway of Sennosides from Senna (Cassia angustifolia Vahl.), a Non-Model Plant with Potent Laxative Properties. PLoS One. 2015 Jun 22;10(6):e0129422.

Chemical & Physical Properties

Density1.7±0.1 g/cm3
Boiling Point1130.3±65.0 °C at 760 mmHg
Molecular FormulaC42H40O19
Molecular Weight848.756
Flash Point344.4±27.8 °C
Exact Mass848.216370
PSA330.89000
LogP0.68
Vapour Pressure0.0±0.3 mmHg at 25°C
Index of Refraction1.758
InChIKeyZFWOUNNKSHIAFK-MIIKWYNKSA-N
SMILESO=C(O)c1cc(O)c2c(c1)C(C1c3cc(CO)cc(O)c3C(=O)c3c(OC4OC(CO)C(O)C(O)C4O)cccc31)c1cccc(OC3OC(CO)C(O)C(O)C3O)c1C2=O
Storage condition2-8°C

Safety Information

RIDADRNONH for all modes of transport

Articles3

More Articles
Potentiating effect of sennoside C on purgative activity of sennoside A in mice.

Planta Med. 42(3) , 302-3, (1981)

The synergistic purgative action of aloe-emodin anthrone and rhein anthrone in mice: synergism in large intestinal propulsion and water secretion.

J. Pharm. Pharmacol. 49(1) , 22-5, (1997)

This study aimed to explore the mechanism involved in the synergistic purgative action of aloe-emodin anthrone and rhein anthrone, the active metabolites of sennoside C. Aloe-emodin anthrone and rhein...

Metabolic activation of sennoside C in mice: synergistic action of anthrones.

J. Pharm. Pharmacol. 44(12) , 973-6, (1992)

Sennosides A and C directly injected into the caecum of mice showed equal purgative activity. Intracaecal administration reduced time to onset of diarrhoea induced by sennoside C from about 3 h after ...

Synonyms

(9R,9'S)-5,5'-Bis(β-D-glucopyranosyloxy)-4,4'-dihydroxy-2'-(hydroxymethyl)-10,10'-dioxo-9,9',10,10'-tetrahydro-9,9'-bianthracene-2-carboxylic acid
[9,9'-Bianthracene]-2-carboxylic acid, 5,5'-bis(β-D-glucopyranosyloxy)-9,9',10,10'-tetrahydro-4,4'-dihydroxy-2'-(hydroxymethyl)-10,10'-dioxo-, (9R,9'S)-
SennosideD
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