Introduction：Basic information about CAS 723-62-6|9-Anthracenecarboxylic acid, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 9-Anthracenecarboxylic acid |
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| CAS Number | 723-62-6 | Molecular Weight | 222.239 |
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| Density | 1.3±0.1 g/cm3 | Boiling Point | 467.5±14.0 °C at 760 mmHg |
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| Molecular Formula | C15H10O2 | Melting Point | 213-217 °C(lit.) |
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| MSDS | ChineseUSA | Flash Point | 206.1±14.8 °C |
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Names
| Name | 9-anthroic acid |
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| Synonym | More Synonyms |
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9-Anthracenecarboxylic acid BiologicalActivity
| Description | Anthracene-9-carboxylic acid (9-Anthracenecarboxylic acid) is an anthracene derivative traditionally used to block and identify Ca2+-activated Cl- currents (CaCCs) in various cell types, like diverse smooth muscle cells, epithelial cells and salivary gland cells[1]. |
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| Related Catalog | Signaling Pathways >>Membrane Transporter/Ion Channel >>Chloride ChannelResearch Areas >>Others |
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| Target | Ca2+-activated Cl- currents[1] |
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| In Vitro | Anthracene-9-carboxylic acid causes a voltage-dependent block of outward currents in HEK 293T cells and inhibits a larger fraction of the current as depolarization increased[1]. Anthracene-9-carboxylic acid induces a strong potentiation of tail currents measured at -100 mV after depolarizing voltages, as well as a prolongation of the deactivation kinetics in HEK 293T[1]. Anthracene-9-carboxylic acid (500 μM, rabbit pulmonary artery smooth muscle cells) produces a small inhibition of the maximum outward Cl- current at +70 mV (21±10%) but augmented the amplitude of the instantaneous inward relaxation at -80 mV by 321±34%[2]. |
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Chemical & Physical Properties
| Density | 1.3±0.1 g/cm3 |
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| Boiling Point | 467.5±14.0 °C at 760 mmHg |
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| Melting Point | 213-217 °C(lit.) |
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| Molecular Formula | C15H10O2 |
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| Molecular Weight | 222.239 |
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| Flash Point | 206.1±14.8 °C |
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| Exact Mass | 222.068085 |
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| PSA | 37.30000 |
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| LogP | 4.36 |
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| Vapour Pressure | 0.0±1.2 mmHg at 25°C |
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| Index of Refraction | 1.743 |
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| InChIKey | XGWFJBFNAQHLEF-UHFFFAOYSA-N |
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| SMILES | O=C(O)c1c2ccccc2cc2ccccc12 |
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| Water Solubility | insoluble |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- CB8764000
- CHEMICAL NAME :
- 9-Anthroic acid
- CAS REGISTRY NUMBER :
- 723-62-6
- LAST UPDATED :
- 199701
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C15-H10-O2
- MOLECULAR WEIGHT :
- 222.25
- WISWESSER LINE NOTATION :
- L C666J BVQ
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 750 mg/kg
- TOXIC EFFECTS :
- Behavioral - rigidity (including catalepsy) Behavioral - muscle contraction or spasticity
MUTATION DATA - TYPE OF TEST :
- Phage inhibition capacity
- TEST SYSTEM :
- Bacteria - Escherichia coli
- DOSE/DURATION :
- 127 ug/well
- REFERENCE :
- MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 260,349,1991
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Safety Information
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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| Hazard Codes | Xi:Irritant |
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| Risk Phrases | R36/37/38 |
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| Safety Phrases | S37/39-S26 |
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| RIDADR | NONH for all modes of transport |
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| WGK Germany | 3 |
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| RTECS | CB8764000 |
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| HS Code | 2916399090 |
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Customs
| HS Code | 2916399090 |
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| Summary | 2916399090 other aromatic monocarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0% |
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Synonyms
| 9-Anthroic acid |
| EINECS 211-964-9 |
| 9-Carboxyanthracene |
| ANCA |
| anthracene-9-carboxylic acid |
| MFCD00001257 |
| 9-Anthracene carboxylic acid |
| anthracenecarboxylic acid |
| 9-Anthracenecarboxylic acid |
| Polyoxyethylenesorbitan monolaurate |
