Introduction：Basic information about CAS 466-26-2|Bullatine B, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Bullatine B |
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| CAS Number | 466-26-2 | Molecular Weight | 437.570 |
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| Density | 1.3±0.1 g/cm3 | Boiling Point | 578.3±50.0 °C at 760 mmHg |
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| Molecular Formula | C24H39NO6 | Melting Point | 159-161 degºC |
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| MSDS | / | Flash Point | 303.5±30.1 °C |
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Names
| Name | Neoline |
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| Synonym | More Synonyms |
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Bullatine B BiologicalActivity
| Description | Neoline, the active ingredient of processed aconite root (PA), alleviated oxaliplatin-induced peripheral neuropathy in mice. Neoline can be used as a marker compound to determine the quality of the PA products for the treatment of neuropathic pain[1]. |
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| Related Catalog | Signaling Pathways >>Others >>OthersResearch Areas >>Neurological Disease |
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| References | [1]. Tanimura Y, et al. Neoline is the active ingredient of processed aconite root against murine peripheral neuropathic pain model, and its pharmacokinetics in rats.J Ethnopharmacol. 2019 Sep 15;241:111859. |
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Chemical & Physical Properties
| Density | 1.3±0.1 g/cm3 |
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| Boiling Point | 578.3±50.0 °C at 760 mmHg |
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| Melting Point | 159-161 degºC |
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| Molecular Formula | C24H39NO6 |
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| Molecular Weight | 437.570 |
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| Flash Point | 303.5±30.1 °C |
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| Exact Mass | 437.277740 |
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| PSA | 91.62000 |
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| LogP | -1.69 |
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| Vapour Pressure | 0.0±3.6 mmHg at 25°C |
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| Index of Refraction | 1.602 |
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| InChIKey | XRARAKHBJHWUHW-RFESQMQVSA-N |
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| SMILES | CCN1CC2(COC)CCC(O)C34C5CC6C(OC)CC(O)(C5C6O)C(C(OC)C23)C14 |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- AR5569450
- CHEMICAL NAME :
- Aconitane-1,8,14-triol, 20-ethyl-6,16-dimethoxy-4-(methoxymethyl)-, (1-alpha,6-alpha,14- alpha,16-beta)-
- CAS REGISTRY NUMBER :
- 466-26-2
- LAST UPDATED :
- 199412
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C24-H39-N-O6
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 150 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- CTYAD8 Zhongcaoyao. Chinese Traditional and Herbal Medicine. (China International Book Trading Corp., POB 2820, Beijing, Peop. Rep. China) V.11- 1980- Volume(issue)/page/year: 15,180,1984
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Synonyms
| Xuan-Wu 3 |
| Dideacetyldelphisine |
| Bullatine B |
| Aconitane-1,8,14-triol, 20-ethyl-6,16-dimethoxy-4-(methoxymethyl)- |
| 20-Ethyl-6,16-dimethoxy-4-(methoxymethyl)aconitane-1,8,14-triol |
