CAS 60-92-4|Adenosine cyclophosphate

Introduction：Basic information about CAS 60-92-4|Adenosine cyclophosphate, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Adenosine cyclophosphate BiologicalActivity
3. Chemical & Physical Properties
4. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
MUTATION DATA
5. Safety Information
6. Articles705
7. Synonyms

Common Name	Adenosine cyclophosphate
CAS Number	60-92-4	Molecular Weight	329.206
Density	2.5±0.1 g/cm3	Boiling Point	701.5±70.0 °C at 760 mmHg
Molecular Formula	C₁₀H₁₂N₅O₆P	Melting Point	260 °C (dec.)(lit.)
MSDS	USA	Flash Point	378.0±35.7 °C

Names

Name	3',5'-cyclic AMP
Synonym	More Synonyms

Adenosine cyclophosphate BiologicalActivity

Description	cAMP is a mitogenic messenger and promotes the G1 to S phase transition in the cell cycle.
Related Catalog	Research Areas >>OthersNatural Products >>Saccharides and Glycosides
Target	Human Endogenous Metabolite
References	[1]. Cook SJ, et al. Inhibition by cAMP of Ras-dependent activation of Raf. Science. 1993 Nov 12;262(5136):1069-72.

Chemical & Physical Properties

Density	2.5±0.1 g/cm3
Boiling Point	701.5±70.0 °C at 760 mmHg
Melting Point	260 °C (dec.)(lit.)
Molecular Formula	C₁₀H₁₂N₅O₆P
Molecular Weight	329.206
Flash Point	378.0±35.7 °C
Exact Mass	329.052521
PSA	164.65000
Vapour Pressure	0.0±2.3 mmHg at 25°C
Index of Refraction	2.012
InChIKey	GXYGERHACAPJMO-MCDZGGTQSA-N
SMILES	Nc1ncnc2c1ncn2C1OC2COP(=O)(O)OC2C1O.O
Water Solubility	50 mg/mL

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: AU7357600

CHEMICAL NAME :: Adenosine, cyclic 3',5'-(hydrogenphosphate)-

CAS REGISTRY NUMBER :: 60-92-4

BEILSTEIN REFERENCE NO. :: 0052645

LAST UPDATED :: 199701

DATA ITEMS CITED :: 6

MOLECULAR FORMULA :: C10-H12-N5-O6-P

MOLECULAR WEIGHT :: 329.24

WISWESSER LINE NOTATION :: T56 BO FOPOTJ DQ GQ GO C- DT56 BN DN FN HNJ IZ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :: Mutation test systems - not otherwise specified

TEST SYSTEM :: Rodent - mouse Fibroblast

DOSE/DURATION :: 500 umol/L

REFERENCE :: IJCNAW International Journal of Cancer. (International Union Against Cancer, 3 rue du Conseil- General, 1205 Geneva, Switzerland) V.1- 1966- Volume(issue)/page/year: 13,404,1974

Safety Information

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes	C:Corrosive
Risk Phrases	R34
Safety Phrases	22-24/25-45-36/37/39-26-36
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	AU7357600

Articles705

H4 histamine receptors inhibit steroidogenesis and proliferation in Leydig cells.

J. Endocrinol. 223(3) , 241-53, (2014)

The histamine H4 receptor (HRH4), discovered only 13 years ago, is considered a promising drug target for allergy, inflammation, autoimmune disorders and cancer, as reflected by a steadily growing num...

Sinensetin enhances adipogenesis and lipolysis by increasing cyclic adenosine monophosphate levels in 3T3-L1 adipocytes.

Biol. Pharm. Bull. 38(4) , 552-8, (2015)

Sinensetin is a rare polymethoxylated flavone (PMF) found in certain citrus fruits. In this study, we investigated the effects of sinensetin on lipid metabolism in 3T3-L1 cells. Sinensetin promoted ad...

Suppression of InsP3 receptor-mediated Ca2+ signaling alleviates mutant presenilin-linked familial Alzheimer's disease pathogenesis.

J. Neurosci. 34(20) , 6910-23, (2014)

Exaggerated intracellular Ca(2+) signaling is a robust proximal phenotype observed in cells expressing familial Alzheimer's disease (FAD)-causing mutant presenilins (PSs). The mechanisms that underlie...

Synonyms

Adenosine 3,5'-cyclic monophosphoric acid

Adenosine 3',5'-cyclic monophosphate

adenosine cyclic-monophosphate

cyclic Adenosine 3',5'-monophosphate

(4aR,6R,7R,7aS)-6-(6-Amino-9H-purin-9-yl)tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinine-2,7-diol 2-oxide

Cyclic AMP

3'5'-cyclic ester of AMP

adenosine-cyclic-phosphate

cyclic 3',5'-AMP

cAMP

Adenosine 3‘,5‘-cyclic monophosphate

Adenosine 3′,5′-cyclic monophosphate

adenosine cyclic 3',5'-phosphate

cyclic Adenosine 3',5'-phosphate

Cyclic 3',5'-adenylate

EINECS 200-492-9

4H-Furo[3,2-d]-1,3,2-dioxaphosphorin-7-ol, 6-(6-amino-9H-purin-9-yl)tetrahydro-2-hydroxy-, 2-oxide, (4aR,6R,7R,7aS)-

3',5'-Cyclic AMP

Adenosine 3',5'-cyclic phosphate

3′,5′-Cyclic AMP

Adenosine-3',5'-cyclicmonophosphate

MFCD00005845

Adenosine cyclic monophosphate

Cyclic adenosine monophosphate

Recommended......